Phf12

Summary

Gene Symbol: Phf12
Description: PHD finger protein 12
Alias: PHD finger protein 12
Species: rat
Products:     Phf12

Top Publications

  1. Yochum G, Ayer D. Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex. Mol Cell Biol. 2001;21:4110-8 pubmed
    ..Pf1 binds TLE in an mSin3A-independent manner and recruits functional TLE complexes to repress transcription. These findings suggest that Pf1 may serve to bridge two global transcription networks, mSin3A and TLE. ..
  2. Park S, Gupta D, Hurwich R, Kim C, Dziarski R. Peptidoglycan recognition protein Pglyrp2 protects mice from psoriasis-like skin inflammation by promoting regulatory T cells and limiting Th17 responses. J Immunol. 2011;187:5813-23 pubmed publisher
    ..Thus, in wild type mice, Pglyrp2 limits overactivation of Th17 cells by promoting accumulation of regulatory T cells at the site of inflammation, which protects the skin from the exaggerated inflammatory response. ..
  3. Kaadige M, Ayer D. The polybasic region that follows the plant homeodomain zinc finger 1 of Pf1 is necessary and sufficient for specific phosphoinositide binding. J Biol Chem. 2006;281:28831-6 pubmed