Gene Symbol: Pecr
Description: peroxisomal trans-2-enoyl-CoA reductase
Alias: TERP, peroxisomal trans-2-enoyl-CoA reductase, PX-2,4-DCR1, RLF98, perosisomal 2-enoyl-CoA reductase, peroxisomal 2,4-dienoyl-CoA reductase
Species: rat
Products:     Pecr

Top Publications

  1. Amery L, Mannaerts G, Subramani S, Van Veldhoven P, Fransen M. Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology. Comb Chem High Throughput Screen. 2001;4:545-52 pubmed
    ..These results further demonstrate the suitability of the gVI-cDNA phage display technology for cDNA expression cloning using an antibody as a probe. ..
  2. Satoh M, Haruta Satoh E, Yamada M, Kado S, Nomura F. Overexpression of hydroxymethylglutaryl CoA synthase 2 and 2,4-dienoyl-CoA reductase in rat pancreas following chronic alcohol consumption. Pancreas. 2013;42:475-82 pubmed publisher
  3. Naylor D, Hoogenraad N, Høj P. Characterisation of several Hsp70 interacting proteins from mammalian organelles. Biochim Biophys Acta. 1999;1431:443-50 pubmed
  4. Zhang J, Underwood L. Molecular cloning and characterization of a new fasting-inducible short-chain dehydrogenase/reductase from rat liver(1). Biochim Biophys Acta. 1999;1435:184-90 pubmed
    We have isolated a 668 bp cDNA from fasted rat liver, designated RLF98, by suppression subtractive hybridization (SSH)...
  5. Das A, Uhler M, Hajra A. Molecular cloning and expression of mammalian peroxisomal trans-2-enoyl-coenzyme A reductase cDNAs. J Biol Chem. 2000;275:24333-40 pubmed publisher
    ..Northern blot analysis demonstrated that a single transcript of 1.3 kilobases is present in most mouse tissues, with particularly high concentrations in liver and kidney...
  6. Gloerich J, Ruiter J, van den Brink D, Ofman R, Ferdinandusse S, Wanders R. Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation. FEBS Lett. 2006;580:2092-6 pubmed
    ..In conclusion, our results show that human TER is responsible for the reduction of phytenoyl-CoA to phytanoyl-CoA in peroxisomes. ..