Gene Symbol: Pcna
Description: proliferating cell nuclear antigen
Alias: PCNAR, Pcna/cyclin, proliferating cell nuclear antigen, cyclin
Species: rat
Products:     Pcna

Top Publications

  1. Wang S, Nakajima Y, Yu Y, Xia W, Chen C, Yang C, et al. Tyrosine phosphorylation controls PCNA function through protein stability. Nat Cell Biol. 2006;8:1359-68 pubmed
    The proliferating cell nuclear antigen (PCNA) is an essential protein for DNA replication and damage repair. How its function is controlled remains an important question...
  2. Moldovan G, Pfander B, Jentsch S. PCNA, the maestro of the replication fork. Cell. 2007;129:665-79 pubmed
    ..b>Proliferating cell nuclear antigen (PCNA)-a cofactor of DNA polymerases that encircles DNA-orchestrates several of these functions by ..
  3. Ohyama C, Ito A, Tokuyama S, Nakazumi H, Suzuki K, Kawamura S, et al. [Clinical significance of proliferating cell nuclear antigen (PCNA) and argyrophilic nucleolar organizer region (AgNOR) in testicular tumors]. Nihon Hinyokika Gakkai Zasshi. 1995;86:1543-51 pubmed
    Proliferative potential of testicular tumor was assessed by immunohistochemistry using anti-proliferating cell nuclear antigen (PCNA) monoclonal antibody and silver staining of argyrophilic nucleolar organizer region (AgNOR), and the ..
  4. D Andrea M, Lawrence D, Nagele R, Wang C, Damiano B. PCNA indexing as a preclinical immunohistochemical biomarker for testicular toxicity. Biotech Histochem. 2008;83:211-20 pubmed publisher
    ..Recently, immunolabeling cells with proliferating cell nuclear antigen (PCNA) has been used to identify proliferating spermatogonia; however, there have been no systematic ..
  5. Hedglin M, Kumar R, Benkovic S. Replication clamps and clamp loaders. Cold Spring Harb Perspect Biol. 2013;5:a010165 pubmed publisher
    ..Here we discuss the structure and composition of sliding clamps and clamp loaders from the three domains of life as well as T4 bacteriophage, and provide our current understanding of the clamp-loading process. ..
  6. Hassan M, Fouad H, Bahashwan S, Al Hendy A. Towards non-surgical therapy for uterine fibroids: catechol-O-methyl transferase inhibitor shrinks uterine fibroid lesions in the Eker rat model. Hum Reprod. 2011;26:3008-18 pubmed publisher
    ..Expressions of Cyclin D1, proliferating cell nuclear antigen (PCNA), Poly [ADP-ribose] polymerase1 (PARP1), tumor suppressor gene (P53) and transforming growth ..
  7. Poot R, Bozhenok L, van den Berg D, Steffensen S, Ferreira F, Grimaldi M, et al. The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci. Nat Cell Biol. 2004;6:1236-44 pubmed
    ..syndrome transcription factor (WSTF) is targeted to replication foci through direct interaction with the DNA clamp PCNA, an important coordinator of DNA and chromatin replication...
  8. Li D, Wang Y, Zhou S, Sun W. ?-lipoic acid exerts neuroprotective effects on neuronal cells by upregulating the expression of PCNA via the P53 pathway in neurodegenerative conditions. Mol Med Rep. 2016;14:4360-4366 pubmed publisher
    ..Previous findings have suggested that proliferating cell nuclear antigen (PCNA), a critical regulatory protein for DNA repair, is involved in dopaminergic neuron damage in ..
  9. Cazzalini O, Sommatis S, Tillhon M, Dutto I, Bachi A, Rapp A, et al. CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. Nucleic Acids Res. 2014;42:8433-48 pubmed publisher
    The proliferating cell nuclear antigen (PCNA) protein serves as a molecular platform recruiting and coordinating the activity of factors involved in multiple deoxyribonucleic acid (DNA) transactions...

More Information


  1. Reed C, Hutcheson J, Mayhew C, Witkiewicz A, Knudsen E. RB tumor suppressive function in response to xenobiotic hepatocarcinogens. Am J Pathol. 2014;184:1853-9 pubmed publisher
    ..These data demonstrate the context specificity of RB and the key role RB plays in the suppression of hepatocellular carcinoma driven by xenobiotic stress. ..
  2. Yang Z, Jakymiw A, Wood M, Eystathioy T, Rubin R, Fritzler M, et al. GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation. J Cell Sci. 2004;117:5567-78 pubmed
    ..By costaining with CENP-F and PCNA, and employing a double-thymidine block to synchronize HeLa cells, GW bodies were observed to be small in early S ..
  3. Sheen Chen S, Ho H, Chen W, Eng H. Obstructive jaundice alters proliferating cell nuclear antigen expression in rat small intestine. World J Surg. 2003;27:1161-4 pubmed
    ..b>Proliferating cell nuclear antigen (PCNA), also known as cyclin, is an auxiliary protein of DNA polymerase-delta, and the level of ..
  4. Li D, Li G, Zhang B, Feng J, Zhao H. Damage to dopaminergic neurons is mediated by proliferating cell nuclear antigen through the p53 pathway under conditions of oxidative stress in a cell model of Parkinson's disease. Int J Mol Med. 2016;37:429-35 pubmed publisher
    ..This process involves a number of signaling cascades and molecular proteins. Proliferating cell nuclear antigen (PCNA) is a pleiotropic protein affecting a wide range of vital cellular processes, including ..
  5. Theocharis S, Skopelitou A, Margeli A, Pavlaki K, Kittas C. Proliferating cell nuclear antigen (PCNA) expression in regenerating rat liver after partial hepatectomy. Dig Dis Sci. 1994;39:245-52 pubmed
    b>Proliferating cell nuclear antigen (PCNA) is a nuclear protein maximally elevated in the S phase of proliferating and transformed cells and is recognized by the monoclonal antibody PC-10 in paraffin tissue sections...
  6. Wu L, Zhang W, Li H, Zhang G, Chen B, Tang Y, et al. [Effects of Buyang Huanwu Decoction and its alkaloids and glycosides on aortic intimal hyperplasia and expression of proliferating cell nuclear antigen in rats with aortic intimal injuries]. Zhong Xi Yi Jie He Xue Bao. 2008;6:836-42 pubmed publisher
    ..of traditional Chinese herbal medicine, on aortic intimal hyperplasia and the expression of the proliferating cell nuclear antigen (PCNA) in rats with aortic intimal injuries...
  7. Arnaiz M, Fichera L, Postan M. Cardiac myocyte hypertrophy and proliferating cell nuclear antigen expression in Wistar rats infected with Trypanosoma cruzi. J Parasitol. 2002;88:919-25 pubmed
    ..b>Proliferating cell nuclear antigen (PCNA) expression, transversal diameter, nuclear area, and number of nuclei per unit volume were ..
  8. Johnson M, Ekonomou A, Hobbs C, Ballard C, Perry R, Perry E. Neurogenic marker abnormalities in the hippocampus in dementia with Lewy bodies. Hippocampus. 2011;21:1126-36 pubmed publisher
    ..neurogenic niche, immunohistochemistry (IHC) using the neural stem cell markers Musashi 1, nestin, proliferating cell nuclear antigen (PCNA), doublecortin, and glial fibrillary acidic protein (GFAP) were examined in age-matched ..
  9. Liu Y, Bambara R. Gene expression of PCNA/cyclin in adult tissues and the R3230AC mammary tumor of rat. Biochem Biophys Res Commun. 1989;161:873-82 pubmed
    We have investigated the gene expression of PCNA (Proliferating Cell Nuclear Antigen)/cyclin in rat tissues and the R3230AC mammary tumor...
  10. Picut C, Swanson C, Scully K, Roseman V, Parker R, Remick A. Ovarian follicle counts using proliferating cell nuclear antigen (PCNA) and semi-automated image analysis in rats. Toxicol Pathol. 2008;36:674-9 pubmed publisher
    ..sections, the use of immunohistochemical methods, including human cytochrome P450 1B1 (CYP1B1) and proliferating cell nuclear antigen (PCNA), have been used to enhance the visibility of the primordial and primary follicles to ..
  11. Chen X, Li J, Zeng L, Zhan Y, Yang Y, Yang Q, et al. [Omega-6 polyunsaturated fatty acid promotes colon carcinogenesis]. Zhonghua Wei Chang Wai Ke Za Zhi. 2010;13:774-7 pubmed
    ..Aberrant crypt focis (ACFs) were observed after methylene blue staining and enumerated. Colonic mucosa PCNA and P53 expressions were assessed by RT-PCR and Western blotting, and location of P53 in the colon crypt focis was ..
  12. Parlanti E, Pascucci B, Terrados G, Blanco L, Dogliotti E. Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase beta-defective mouse cells. DNA Repair (Amst). 2004;3:703-10 pubmed
    ..We present evidence that short-patch repair synthesis occurs even in the absence of both Pol beta and replicative Pols. Exogeneously added purified human Pol lambda was unable to stimulate this back-up synthesis. ..
  13. Terai K, Abbas T, Jazaeri A, Dutta A. CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis. Mol Cell. 2010;37:143-9 pubmed publisher
    Monoubiquitination of proliferating cell nuclear antigen (PCNA) is a critical posttranslational modification essential for DNA repair by translesion DNA synthesis (TLS)...
  14. Rountree M, Bachman K, Baylin S. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet. 2000;25:269-77 pubmed
    ..Thus, DNMT1 not only maintains DNA methylation, but also may directly target, in a heritable manner, transcriptionally repressive chromatin to the genome during DNA replication. ..
  15. Tahan S, Neuberg D, Dieffenbach A, Yacoub L. Prediction of early relapse and shortened survival in patients with breast cancer by proliferating cell nuclear antigen score. Cancer. 1993;71:3552-9 pubmed
    ..The recent discovery of the S-phase-specific nuclear protein proliferating cell nuclear antigen (PCNA) opens the door for a novel approach to cell kinetic measurement with an immunocytochemical ..
  16. Gerzanich V, Ivanova S, Van Der Heijden M, Zhou H, Simard J. Trans-cellular proliferating cell nuclear antigen gene activation in cerebral vascular smooth muscle by endothelial oxidative injury in vivo. Arterioscler Thromb Vasc Biol. 2003;23:2048-54 pubmed
    ..in endothelium, consistent with oxidant stress; (2) the fraction of VSMC nuclei labeled for proliferating cell nuclear antigen (PCNA) increased 7-fold at 6 hours, preceded by a several-fold increase in nuclear phospho-cAMP-..
  17. Tazuke Y, Maeda K, Wasa M, Satoko N, Fukuzawa M. Protective mechanism of glutamine on the expression of proliferating cell nuclear antigen after cisplatin-induced intestinal mucosal injury. Pediatr Surg Int. 2011;27:151-8 pubmed publisher
    ..However, the mechanism has not yet been elucidated. Proliferating cell nuclear antigen (PCNA) is expressed in the nuclei of cells during the DNA synthesis phase of the cell cycle, and ..
  18. Zhou J, Hu X, Xiong X, Liu X, Liu Y, Ren K, et al. Cloning of two rat PDIP1 related genes and their interactions with proliferating cell nuclear antigen. J Exp Zool A Comp Exp Biol. 2005;303:227-40 pubmed
    ..is a tumor necrosis factor alpha and interleukin 6 inducible protein that interacts directly with proliferating cell nuclear antigen (PCNA) and the small subunit (p50) of DNA polymerase delta...
  19. Celeste A, Petersen S, Romanienko P, Fernandez Capetillo O, Chen H, Sedelnikova O, et al. Genomic instability in mice lacking histone H2AX. Science. 2002;296:922-7 pubmed
    ..Thus, H2AX is critical for facilitating the assembly of specific DNA-repair complexes on damaged DNA. ..
  20. Colley S, Wintle L, Searles R, Russell V, Firman R, Smith S, et al. Loss of the nuclear receptor corepressor SLIRP compromises male fertility. PLoS ONE. 2013;8:e70700 pubmed publisher
    ..In sum, our data implicates SLIRP in regulating male fertility, wherein its loss results in asthenozoospermia associated with compromised sperm structure and mitochondrial morphology. ..
  21. Weng J, Yung B. Nucleophosmin/B23 regulates PCNA promoter through YY1. Biochem Biophys Res Commun. 2005;335:826-31 pubmed
    ..caused a marked up-regulation in the amounts of Yin Yang 1 (YY1) and proliferating cellular nuclear antigen (PCNA) proteins...
  22. Jiang Q, Song X, Cui Q, Chen L. [Effect of fluoride on expression of telomerase reverse transcriptase expression and proliferating cell nuclear antigen in germ cells of rats' testes]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2007;25:96-9 pubmed
    ..The change of telomerase reverse transcriptase(TERT) and proliferating cell nuclear antigen (PCNA) were observed by using in situ hybridization and radioimmunoassay respectively...
  23. Kwon J, Kikuchi T, Setsuie R, Ishii Y, Kyuwa S, Yoshikawa Y. Characterization of the testis in congenitally ubiquitin carboxy-terminal hydrolase-1 (Uch-L1) defective (gad) mice. Exp Anim. 2003;52:1-9 pubmed
    ..By immunohistochemistry, a significant decrease (p < 0.05) in the number of proliferating cell nuclear antigen (PCNA) positive cells was observed...
  24. Levavasseur F, Burbelo P, Cariou S, Lietard J, Yamada Y, Clement B. Nuclear recruitment of A1p145 subunit of replication factor C in the early G1 phase of the cell cycle in Faza 567 hepatoma cell line and hepatocyte primary cultures. FEBS Lett. 1995;363:132-6 pubmed
    ..revealed that the large subunit of replication factor C (A1p145; mRFC140) was in a complex with proliferating cell nuclear antigen (PCNA)...
  25. Moldovan G, Madhavan M, Mirchandani K, McCaffrey R, Vinciguerra P, D Andrea A. DNA polymerase POLN participates in cross-link repair and homologous recombination. Mol Cell Biol. 2010;30:1088-96 pubmed publisher
    ..Our data indicate that this novel polymerase-helicase complex participates in homologous recombination repair and is essential for cellular protection against DNA cross-links. ..
  26. Imai H, Harland J, McCulloch J, Graham D, Brown S, Macrae I. Specific expression of the cell cycle regulation proteins, GADD34 and PCNA, in the peri-infarct zone after focal cerebral ischaemia in the rat. Eur J Neurosci. 2002;15:1929-36 pubmed
    ..Expression of growth arrest and DNA damage-inducible protein, GADD34 and proliferating cell nuclear antigen (PCNA) have been investigated in the core and peri-infarct zone at 2 and 24 h after middle cerebral ..
  27. Koike E, Hirano S, Shimojo N, Kobayashi T. cDNA microarray analysis of gene expression in rat alveolar macrophages in response to organic extract of diesel exhaust particles. Toxicol Sci. 2002;67:241-6 pubmed
    ..peroxidase 2 (TDPX-2), glutathione S-transferase P subunit (GST-P), NAD(P)H dehydrogenase, and proliferating cell nuclear antigen (PCNA)...
  28. Kayisli U, Berkkanoglu M, Kizilay G, Senturk L, Arici A. Expression of proliferative and preapoptotic molecules in human myometrium and leiomyoma throughout the menstrual cycle. Reprod Sci. 2007;14:678-86 pubmed
    ..investigate Fas ligand (FasL), phosphatase and tensin homolog deletion on chromosome 10 (PTEN), and proliferating cell nuclear antigen (PCNA) expression in myometrium and leiomyoma...
  29. Jaime M, Pujol M, Serratosa J, Pantoja C, Canela N, Casanovas O, et al. The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers. Hepatology. 2002;35:1063-71 pubmed
    ..These cells also show a premature induction of cyclin E/cyclin-dependent kinase (CDK) 2 activity...
  30. Xu L, Li J, Sun M, Sun H. Expression of intestinal trefoil factor, proliferating cell nuclear antigen and histological changes in intestine of rats after intrauterine asphyxia. World J Gastroenterol. 2005;11:2291-5 pubmed
    To study the expressions of intestinal trefoil factor (ITF) and proliferating cell nuclear antigen (PCNA) and histologic changes in intestine, to investigate the relationship between ITF and intestinal damage and repair after intrauterine ..
  31. Okada M, Sakaguchi T, Kawasaki K. Proliferating cell nuclear antigen in neurones: induction by u.v. irradiation. Neuroreport. 1996;7:1770-2 pubmed
    b>Proliferating cell nuclear antigen (PCNA) plays a pleiotropic role in DNA replication, excision repair of injured DNA and apoptosis...
  32. Yu S, Liu H, Ling Ling E, Wang D, Zhu G. Proliferation and differentiation of osteoblasts from the mandible of osteoporotic rats. Exp Biol Med (Maywood). 2012;237:395-406 pubmed publisher
    ..Transmission electron microscopy (TEM) was performed to assess differences in the ultrastructure. Proliferating cell nuclear antigen (PCNA) and uncoupling protein 2 (UCP2) protein concentrations were analyzed by Western blot...
  33. Shillingford J, Miyoshi K, Flagella M, Shull G, Hennighausen L. Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis. Mol Endocrinol. 2002;16:1309-21 pubmed
  34. Horner A, Shum L, Ayres J, Nonaka K, Nuckolls G. Fibroblast growth factor signaling regulates Dach1 expression during skeletal development. Dev Dyn. 2002;225:35-45 pubmed
    ..Dach1 also colocalized with cyclin-dependent kinase inhibitors p27 (Kip1) and p57 (Kip2) in chondrocytes of the growth plate and in the epiphysis ..
  35. Solanas M, Grau L, Moral R, Vela E, Escrich R, Escrich E. Dietary olive oil and corn oil differentially affect experimental breast cancer through distinct modulation of the p21Ras signaling and the proliferation-apoptosis balance. Carcinogenesis. 2010;31:871-9 pubmed publisher
    ..We analyzed the tumor mitotic index, proliferating cell nuclear antigen (PCNA) levels, and apoptosis through Caspase-3 analysis and terminal deoxynucleotidyl transferase-..
  36. Stubbe J, Madsen K, Nielsen F, Sk√łtt O, Jensen B. Glucocorticoid impairs growth of kidney outer medulla and accelerates loop of Henle differentiation and urinary concentrating capacity in rat kidney development. Am J Physiol Renal Physiol. 2006;291:F812-22 pubmed
    ..Proliferating-cell nuclear antigen (PCNA)-positive cells shifted from the nephrogenic zone in the first postnatal week to Tamm-Horsfall-positive thick ..
  37. Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A. PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes Dev. 2008;22:2496-506 pubmed publisher
    The DNA polymerase delta processivity factor Proliferating Cell Nuclear Antigen (PCNA) promotes the DNA damage-induced degradation of the replication initiation factor Cdt1 via the CRL4(Cdt2) E3 ubiquitin ligase complex...
  38. Richter K, Brar S, Ray M, Pisitkun P, Bolland S, Verkoczy L, et al. Speckled-like pattern in the germinal center (SLIP-GC), a nuclear GTPase expressed in activation-induced deaminase-expressing lymphomas and germinal center B cells. J Biol Chem. 2009;284:30652-61 pubmed publisher
    ..These results strongly suggest that SLIP-GC is a replication-related protein in germinal center B cells whose reduction is toxic to cells through an AID-dependent mechanism. ..
  39. Gao Y, Lu Y, Mi S, Liu X, Su G, Rong S. Change of p16(INK4a) and PCNA protein expression in myocardium after injection of hIGF-1 gene modified skeletal myoblasts into post-infarction rats. J Huazhong Univ Sci Technolog Med Sci. 2008;28:396-400 pubmed publisher
    This study examined the change of p16(INK4a) and PCNA protein expression in myocardium after injection of hIGF-1 gene modified skeletal myoblasts into post-infarction rats...
  40. Romeu L, da Motta E, Maganhin C, Oshima C, Fonseca M, Barrueco K, et al. Effects of melatonin on histomorphology and on the expression of steroid receptors, VEGF, and PCNA in ovaries of pinealectomized female rats. Fertil Steril. 2011;95:1379-84 pubmed publisher
    ..ovaries of pinealectomized female rats through histomorphometric analysis and on steroid receptors, proliferating cell nuclear antigen (PCNA), and vascular endothelial growth factor (VEGF) expression. Experimental study...
  41. Niu Y, Fu X, Zhao Y. [The expression of proliferating cell nuclear antigen in breast phylloides cystosarcoma and its significance]. Zhonghua Bing Li Xue Za Zhi. 1997;26:337-9 pubmed
    To investigate the expression of proliferating cell nuclear antigen (PCNA) in breast phylloides cystosarcoma and its clinicopathological signification...
  42. Wang Z, Chang X, Fu X, Sun T, Yang Y, Chen W, et al. [Expression of protooncogene c-jun, p38 and proliferating cell nuclear antigen in intestinal epithelial cells in rats different development stages]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2003;15:77-80 pubmed
    ..Immunohistochemical techniques were used to detect the expressions of c-jun, p38 and proliferating cell nuclear antigen (PCNA)...
  43. Yu F, Han C, Yang W, Jin X, Hu Z, Liu Y. Role of ERK1/2 in FSH induced PCNA expression and steroidogenesis in granulosa cells. Front Biosci. 2005;10:896-904 pubmed
    ..whether FSH activated ERK1/2 was involved in the regulation of the proliferation related gene proliferating cell nuclear antigen (PCNA) and steroidogenesis...
  44. Amare Kadam P, Varghese C, Bharde S, Narasimhamoorthy N, Desai S, Advani S, et al. Proliferating cell nuclear antigen and epidermal growth factor receptor (EGFr) status in renal cell carcinoma patients with polysomy of chromosome 7. Cancer Genet Cytogenet. 2001;125:139-46 pubmed
    ..Both proliferating cell nuclear antigen (PCNA) and EGFr expression were examined in paraffin sections by immunostaining...
  45. Marino T, Cao W, Lee J, Courtney R. Localization of proliferating cell nuclear antigen in the developing and mature rat heart cell. Anat Rec. 1996;245:677-84 pubmed
    ..One protein requisite for DNA synthesis is proliferating cell nuclear antigen (PCNA). This protein is the auxiliary protein of DNA polymerase delta...
  46. Holmes E, Bingham C, Cunningham M. Hepatic expression of polymerase beta, Ref-1, PCNA, and Bax in WY 14,643-exposed rats and hamsters. Exp Mol Pathol. 2002;73:209-19 pubmed
    The hepatic levels of three protein markers of oxidative stress, polymerase beta, Ref-1, and PCNA, and of the pro-apoptotic protein, Bax, were quantitated after exposure to WY 14,643 (500 ppm in the feed) for 6 or 34 days in a rodent that ..
  47. Vannier J, Sandhu S, Petalcorin M, Wu X, Nabi Z, Ding H, et al. RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science. 2013;342:239-42 pubmed publisher
    ..We established that RTEL1 also associates with the replisome through binding to proliferating cell nuclear antigen (PCNA)...
  48. Adolphe C, Hetherington R, Ellis T, Wainwright B. Patched1 functions as a gatekeeper by promoting cell cycle progression. Cancer Res. 2006;66:2081-8 pubmed
    ..of Ptch1, however, a large proportion of basal cells exhibit nuclear accumulation of the cell cycle regulators cyclin D1 and B1...
  49. Chen J, Silver D, Walpita D, Cantor S, Gazdar A, Tomlinson G, et al. Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. Mol Cell. 1998;2:317-28 pubmed
    ..Like BRCA1 and RAD51, BRCA2 relocates to PCNA+ replication sites following exposure of S phase cells to hydroxyurea or UV irradiation...
  50. Deng X, Wei H, Lou D, Sun B, Chen H, Zhang Y, et al. Changes in CLIP3 expression after sciatic nerve injury in adult rats. J Mol Histol. 2012;43:669-79 pubmed publisher
    ..Western blot analyses revealed prominent up-regulation of CLIP3 and PCNA (proliferating cell nuclear antigen) protein levels at 3 days after SNI...
  51. Amasaki H, Ogawa M, Nagasao J, Mutoh K, Ichihara N, Asari M, et al. Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae. Ann Anat. 2003;185:517-23 pubmed
    ..BrdU) and the expression of molecules involved in the control of cell proliferation (proliferating cell nuclear antigen [PCNA], a cellular factor in F9 teratocarcinoma cells that recognizes an adenovirus E1A inducible ..
  52. Sakai Y, Suetake I, Itoh K, Mizugaki M, Tajima S, Yamashina S. Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo. Cell Struct Funct. 2001;26:685-91 pubmed
    ..5-18.5 dpc. The expression profiles of Dnmt1 were similar to that of proliferating cell nuclear antigen (PCNA), a marker for proliferating cells, suggesting that Dnmt1 was specifically expressed in the ..
  53. Yu X, Zhu S, Xu Z, Hu X, Zhu T, Chen J, et al. Roles of EGFR-Stat3 signal pathway in carcinogenesis of experimental hepatoma in rats. J Cancer Res Clin Oncol. 2007;133:145-52 pubmed
    ..In HCC, there was positive correlation between p-Stat3 level and the expression of TGFalpha and PCNA. Increased expression of Bcl-2 (P < 0.05) coincided with elevated level of p-Stat3...