Gene Symbol: Nnat
Description: neuronatin
Alias: Peg5, neuronatin, neuronatin alpha
Species: rat
Products:     Nnat

Top Publications

  1. Joseph R, Dou D, Tsang W. Molecular cloning of a novel mRNA (neuronatin) that is highly expressed in neonatal mammalian brain. Biochem Biophys Res Commun. 1994;201:1227-34 pubmed
    ..The full length cDNA, neuronatin, was 1195bp long and coded for a novel protein of 81 amino acids...
  2. Joseph R, Dou D, Tsang W. Neuronatin mRNA: alternatively spliced forms of a novel brain-specific mammalian developmental gene. Brain Res. 1995;690:92-8 pubmed
    ..Therefore, we investigated the role of neuronatin, a novel cDNA that we cloned from neonatal rat brain (Joseph et al., Biochem. Biophys. Res. Commun...
  3. Chu K, Tsai M. Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes. 2005;54:1064-73 pubmed
    ..Using microarray technology, we identified neuronatin (Nnat) as differentially expressed between wild-type (WT) and knockout (KO) pancreatic RNA from embryonic day 14 ..
  4. Chen K, Yang C, Cheng J, Wu C, Sy W, Lin C. Altered neuronatin expression in the rat dorsal root ganglion after sciatic nerve transection. J Biomed Sci. 2010;17:41 pubmed publisher
    ..Among them, neuronatin (Nnat) was the one which expression was significantly up-regulated...
  5. Joseph R, Tsang W, Dou D, Nelson K, Edvardsen K. Neuronatin mRNA in PC12 cells: downregulation by nerve growth factor. Brain Res. 1996;738:32-8 pubmed
    b>Neuronatin was recently cloned from neonatal rat brain (Biochem, Biophys. Res. Commun., 201 (1994) 1227-1234)...
  6. Vrang N, Meyre D, Froguel P, Jelsing J, Tang Christensen M, Vatin V, et al. The imprinted gene neuronatin is regulated by metabolic status and associated with obesity. Obesity (Silver Spring). 2010;18:1289-96 pubmed publisher
    Using restriction fragment differential display (RFDD) technology, we have identified the imprinted gene neuronatin (Nnat) as a hypothalamic target under the influence of leptin...
  7. Iida S, Hara T, Araki D, Ishimine Kuroda C, Kurozumi A, Sakamoto S, et al. Memory-related gene expression profile of the male rat hippocampus induced by teeth extraction and occlusal support recovery. Arch Oral Biol. 2014;59:133-41 pubmed publisher
    ..analysis revealed that thyrotropin-releasing hormone (Trh) and tenascin XA (Tnxa) were up-regulated and neuronatin (Nnat) and S100a9 were down-regulated after the maze training...
  8. Oyang E, Davidson B, Lee W, Poon M. Functional characterization of the dendritically localized mRNA neuronatin in hippocampal neurons. PLoS ONE. 2011;6:e24879 pubmed publisher
    ..One such transcript encodes the protein neuronatin. Neuronatin has been shown to regulate calcium levels in non-neuronal cells such as pancreatic or embryonic stem ..
  9. Yamashita M, Glasgow E, Zhang B, Kusano K, Gainer H. Identification of cell-specific messenger ribonucleic acids in oxytocinergic and vasopressinergic magnocellular neurons in rat supraoptic nucleus by single-cell differential hybridization. Endocrinology. 2002;143:4464-76 pubmed
    ..These were identified as paternally expressed gene (Peg)5/neuronatin, metallothionein III, Peg3, synaptotagmin V, and a 3'-phosphoadenosine 5'-phosphosulfate synthase 2-related mRNA...