NEWGENE_1309258

Summary

Gene Symbol: NEWGENE_1309258
Description: VPS37C, ESCRT-I subunit
Alias: vacuolar protein sorting-associated protein 37C
Species: rat

Top Publications

  1. Morita E, Sandrin V, Alam S, Eckert D, Gygi S, Sundquist W. Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding. Cell Host Microbe. 2007;2:41-53 pubmed
    ..Taken together, these studies define the composition of human ESCRT-I complexes and indicate that the MVB12 subunits play a unique role in regulating ESCRT-mediated virus budding. ..
  2. Agromayor M, Soler N, Caballe A, Kueck T, Freund S, Allen M, et al. The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. Structure. 2012;20:414-28 pubmed publisher
  3. Okumura M, Katsuyama A, Shibata H, Maki M. VPS37 isoforms differentially modulate the ternary complex formation of ALIX, ALG-2, and ESCRT-I. Biosci Biotechnol Biochem. 2013;77:1715-21 pubmed
    ..The results of in vitro binding assays using purified recombinant proteins indicated that ALG-2 functions as a Ca²?-dependent adaptor protein that bridges ALIX and ESCRT-I to form a ternary complex, ESCRT-I/ALIX/ALG-2. ..