Gene Symbol: Ncapd3
Description: non-SMC condensin II complex, subunit D3
Alias: condensin-2 complex subunit D3
Species: rat
Products:     Ncapd3

Top Publications

  1. Ono T, Losada A, Hirano M, Myers M, Neuwald A, Hirano T. Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells. Cell. 2003;115:109-21 pubmed
    ..We propose that the two condensin complexes make distinct mechanistic contributions to mitotic chromosome architecture in vertebrate cells. ..
  2. Manning A, Longworth M, Dyson N. Loss of pRB causes centromere dysfunction and chromosomal instability. Genes Dev. 2010;24:1364-76 pubmed publisher
    ..These observations explain an important consequence of RB1 inactivation, and suggest that subtle defects in centromere function are a frequent source of merotely and CIN in cancer. ..
  3. Liu W, Tanasa B, Tyurina O, Zhou T, Gassmann R, Liu W, et al. PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature. 2010;466:508-12 pubmed publisher two non-structural maintenance of chromosomes (SMC) condensin II subunits, N-CAPD3 and N-CAPG2 (also known as NCAPD3 and NCAPG2, respectively), are capable of recognizing H4K20me1, and ChIP-Seq analysis demonstrates a significant ..
  4. Lee J, Ogushi S, Saitou M, Hirano T. Condensins I and II are essential for construction of bivalent chromosomes in mouse oocytes. Mol Biol Cell. 2011;22:3465-77 pubmed publisher