Myo1e

Summary

Gene Symbol: Myo1e
Description: myosin IE
Alias: MYR5, Myr3, unconventional myosin-Ie, Unconventional myosin from rat 5, myosin heavy chain myr 3, myosin-Ie, unconventional myosin 1E
Species: rat
Products:     Myo1e

Top Publications

  1. Huber L, Fialka I, Paiha K, Hunziker W, Sacks D, Bahler M, et al. Both calmodulin and the unconventional myosin Myr4 regulate membrane trafficking along the recycling pathway of MDCK cells. Traffic. 2000;1:494-503 pubmed
    ..Altogether, our data indicate that trafficking at early steps of the endocytic pathway in Madin-Darby Canine Kidney cells depends on the actin-based mechanoenzyme myr4, its light chain CaM, and polymerized actin. ..
  2. Benesh A, Nambiar R, McConnell R, Mao S, Tabb D, Tyska M. Differential localization and dynamics of class I myosins in the enterocyte microvillus. Mol Biol Cell. 2010;21:970-8 pubmed publisher
  3. Stoffler H, Ruppert C, Reinhard J, Bahler M. A novel mammalian myosin I from rat with an SH3 domain localizes to Con A-inducible, F-actin-rich structures at cell-cell contacts. J Cell Biol. 1995;129:819-30 pubmed
    ..Incubation of NRK cells with Con A stimulated the formation of myr 3-containing structures along cell-cell contacts. These results suggest for myr 3 a function mediated by cell-cell contact. ..
  4. El Mezgueldi M, Tang N, Rosenfeld S, Ostap E. The kinetic mechanism of Myo1e (human myosin-IC). J Biol Chem. 2002;277:21514-21 pubmed
    b>Myo1e is the widely expressed subclass-1 member of the myosin-I family. We performed a kinetic analysis of a truncated myo1e that consists of the motor and the single IQ motif with a bound calmodulin...
  5. Dumont R, Zhao Y, Holt J, Bähler M, Gillespie P. Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia. J Assoc Res Otolaryngol. 2002;3:375-89 pubmed
    ..Myo1c (myosin-Ib or myr 2). and Myo1e (myr 3). By contrast, Myo1a (brush-border myosin-I), Myo1d (myosin lg or myr 4)...
  6. Krendel M, Osterweil E, Mooseker M. Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis. FEBS Lett. 2007;581:644-50 pubmed
    ..two proteins with prominent functions in endocytosis, synaptojanin-1 and dynamin, bind to the SH3 domain of human Myo1E. Myosin 1E co-localizes with clathrin- and dynamin-containing puncta at the plasma membrane and this co-..
  7. Krendel M, Kim S, Willinger T, Wang T, Kashgarian M, Flavell R, et al. Disruption of Myosin 1e promotes podocyte injury. J Am Soc Nephrol. 2009;20:86-94 pubmed publisher
    Myosin 1e (Myo1e) is one of two Src homology 3 domain-containing "long-tailed" type I myosins in vertebrates, whose functions in health and disease are incompletely understood...
  8. Feeser E, Ignacio C, Krendel M, Ostap E. Myo1e binds anionic phospholipids with high affinity. Biochemistry. 2010;49:9353-60 pubmed publisher
    b>Myo1e is a single-headed motor protein that has been shown to play roles in clathrin-mediated endocytosis in HeLa cells and podocyte function in the kidney...

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