Gene Symbol: Mir125a
Description: microRNA 125a
Balakrishnan A, Stearns A, Park P, Dreyfuss J, Ashley S, Rhoads D, et al
. Upregulation of proapoptotic microRNA mir-125a after massive small bowel resection in rats. Ann Surg. 2012;255:747-53 pubmed publisher
..Our data highlight a potential role for microRNAs as mediators of the adaptive process and may facilitate the development of new therapeutic options for short bowel syndrome. ..
Hu Z, Shen W, Kraemer F, Azhar S. MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in steroidogenic cells. Mol Cell Biol. 2012;32:5035-45 pubmed publisher
Davis C, Clinton J, Krueger J. MicroRNA 138, let-7b, and 125a inhibitors differentially alter sleep and EEG delta-wave activity in rats. J Appl Physiol (1985). 2012;113:1756-62 pubmed publisher
Dong Y, Li P, Ni Y, Zhao J, Liu Z. Decreased microRNA-125a-3p contributes to upregulation of p38 MAPK in rat trigeminal ganglions with orofacial inflammatory pain. PLoS ONE. 2014;9:e111594 pubmed publisher
..Taken together, our results show that miR-125a-3p is negatively correlated with the development and maintenance of orofacial inflammatory pain via regulating p38 MAPK. ..
Gareri C, Iaconetti C, Sorrentino S, Covello C, de Rosa S, Indolfi C. miR-125a-5p Modulates Phenotypic Switch of Vascular Smooth Muscle Cells by Targeting ETS-1. J Mol Biol. 2017;429:1817-1828 pubmed publisher
..Thus, miR-125a-5p in this context inhibits PDGF-BB pathway and is therefore a potential regulator of VSMCs phenotypic switch. ..
Li R, Yin F, Guo Y, Zhao K, Ruan Q, Qi Y. Knockdown of ANRIL aggravates H2O2-induced injury in PC-12 cells by targeting microRNA-125a. Biomed Pharmacother. 2017;92:952-961 pubmed publisher
..This might provide novel insights in the role of ANRIL in pathogenesis of oxidative damage during SCI. ..