Mcm9

Summary

Gene Symbol: Mcm9
Description: minichromosome maintenance 9 homologous recombination repair factor
Alias: RGD1560557, DNA helicase MCM9, minichromosome maintenance complex component 9
Species: rat
Products:     Mcm9

Top Publications

  1. Nishimura K, Ishiai M, Horikawa K, Fukagawa T, Takata M, Takisawa H, et al. Mcm8 and Mcm9 form a complex that functions in homologous recombination repair induced by DNA interstrand crosslinks. Mol Cell. 2012;47:511-22 pubmed publisher
    ..Here, we showed that the replicative helicase-related Mcm family of proteins, Mcm8 and Mcm9, forms a complex required for HR repair induced by ICLs...
  2. Lutzmann M, Grey C, Traver S, Ganier O, Maya Mendoza A, Ranisavljevic N, et al. MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination. Mol Cell. 2012;47:523-34 pubmed publisher
    We generated knockout mice for MCM8 and MCM9 and show that deficiency for these genes impairs homologous recombination (HR)-mediated DNA repair during gametogenesis and somatic cells cycles...
  3. Hartford S, Luo Y, Southard T, Min I, Lis J, Schimenti J. Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression. Proc Natl Acad Sci U S A. 2011;108:17702-7 pubmed publisher
    ..Many eukaryotes have a divergent paralog, MCM9, that was reported to be essential for loading MCM2-7 onto replication origins in the Xenopus oocyte extract system...