Map9

Summary

Gene Symbol: Map9
Description: microtubule-associated protein 9
Alias: Mtap9, RGD1560368, microtubule-associated protein 9
Species: rat

Top Publications

  1. Saffin J, Venoux M, Prigent C, Espeut J, Poulat F, Giorgi D, et al. ASAP, a human microtubule-associated protein required for bipolar spindle assembly and cytokinesis. Proc Natl Acad Sci U S A. 2005;102:11302-7 pubmed
    ..These results suggest a crucial role for ASAP in the organization of the bipolar mitotic spindle, mitosis progression, and cytokinesis and define ASAP as a key factor for proper spindle assembly. ..
  2. Venoux M, Delmouly K, Milhavet O, Vidal EycheniƩ S, Giorgi D, Rouquier S. Gene organization, evolution and expression of the microtubule-associated protein ASAP (MAP9). BMC Genomics. 2008;9:406 pubmed publisher
    ..It may have a role in spermatogenesis and also represents a potential new target for antitumoral drugs. Possible involvement in neuron dynamics also highlights ASAP as a candidate target in neurodegenerative diseases. ..
  3. Gumy L, Katrukha E, Grigoriev I, Jaarsma D, Kapitein L, Akhmanova A, et al. MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons. Neuron. 2017;94:347-362.e7 pubmed publisher
    ..We propose that selective axonal cargo trafficking requires the MAP2-defined pre-axonal filtering zone and the ability of cargos to switch between distinct kinesin motor activities. ..