Gene Symbol: Lamp3
Description: lysosomal-associated membrane protein 3
Alias: lysosome-associated membrane glycoprotein 3, LAMP-3
Salaun B, de Saint Vis B, Pacheco N, Pacheco Y, Riesler A, Isaac S, et al
. CD208/dendritic cell-lysosomal associated membrane protein is a marker of normal and transformed type II pneumocytes. Am J Pathol. 2004;164:861-71 pubmed
..Furthermore, DC-LAMP appears to be a marker of transformed type II pneumocytes as well, an observation that may help the study and the classification of human lung adenocarcinomas...
Mine K, Shulzhenko N, Yambartsev A, Rochman M, Sanson G, Lando M, et al
. Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer. Nat Commun. 2013;4:1806 pubmed publisher
..These findings may help to explain the paradox of episomal human papillomavirus decline in women with invasive cancer who were previously unable to clear the virus. ..
Salaun B, de Saint Vis B, Clair Moninot V, Pin J, Barthélemy Dubois C, Kissenpfennig A, et al
. Cloning and characterization of the mouse homologue of the human dendritic cell maturation marker CD208/DC-LAMP. Eur J Immunol. 2003;33:2619-29 pubmed
..In conclusion, mouse DC-LAMP is not a marker of mature mouse DC and this observation raises new questions regarding the role of human DC-LAMP in human DC. ..
Zhou Z, Xue Q, Wan Y, Yang Y, Wang J, Hung T. Lysosome-associated membrane glycoprotein 3 is involved in influenza A virus replication in human lung epithelial (A549) cells. Virol J. 2011;8:384 pubmed publisher
..We demonstrated that LAMP3, a member of lysosome-associated membrane glycoprotein (LAMP) family, was significantly induced in human lung ..
White C, Yuan X, Schmidt P, Bresciani E, Samuel T, Campagna D, et al
. HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis. Cell Metab. 2013;17:261-70 pubmed publisher
..Our results reveal HRG1 as the long-sought heme transporter for heme-iron recycling in macrophages and suggest that genetic variations in HRG1 could be modifiers of human iron metabolism. ..
Albrecht S, Usmani S, Dietl P, Wittekindt O. Plasma membrane trafficking in alveolar type II cells. Cell Physiol Biochem. 2010;25:81-90 pubmed publisher
..We conclude that secretagogues facilitate the transport of plasma membrane components to LBs via a clathrin-independent vesicular transport pathway. ..
Domínguez Bautista J, Klinkenberg M, Brehm N, Subramaniam M, Kern B, Roeper J, et al
. Loss of lysosome-associated membrane protein 3 (LAMP3) enhances cellular vulnerability against proteasomal inhibition. Eur J Cell Biol. 2015;94:148-61 pubmed publisher
..Another member of the LAMP family is LAMP3, which is expressed only in certain cell types and differentiation stages...