Klrc1

Summary

Gene Symbol: Klrc1
Description: killer cell lectin like receptor C1
Alias: rNKG2A, killer cell lectin-like receptor subfamily C, member 1, natural killer cell protein group 2-A (NKG2A)
Species: rat
Products:     Klrc1

Top Publications

  1. Berg S, Dissen E, Westgaard I, Fossum S. Two genes in the rat homologous to human NKG2. Eur J Immunol. 1998;28:444-50 pubmed
  2. Kaiser B, Pizarro J, Kerns J, Strong R. Structural basis for NKG2A/CD94 recognition of HLA-E. Proc Natl Acad Sci U S A. 2008;105:6696-701 pubmed publisher
    ..Thus, the evolution of the NKG2x/CD94 family of receptors has likely been shaped both by the need to bind the invariant HLA-E ligand and the need to avoid subversion by pathogen-derived decoys. ..
  3. Koike J, Wakao H, Ishizuka Y, Sato T, Hamaoki M, Seino K, et al. Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I. J Exp Med. 2004;199:137-44 pubmed
    ..NKG2I is a novel activating receptor mediating recognition and rejection of allogeneic target cells. ..
  4. Liu J, Liu S, Xia M, Xu S, Wang C, Bao Y, et al. Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation. Proc Natl Acad Sci U S A. 2013;110:7814-9 pubmed publisher
    ..Our study outlines a mechanism for the negative regulation of NK cell activation and also provides clues for the function of the rhomboid proteins in immunity. ..