Kcng1

Summary

Gene Symbol: Kcng1
Description: potassium voltage-gated channel modifier subfamily G member 1
Alias: Kh2, Kv6.1, potassium voltage-gated channel subfamily G member 1, potassium channel, voltage-gated modifier subfamily G, member 1, potassium voltage-gated channel, subfamily G, member 1, voltage-gated potassium channel subunit Kv6.1
Species: rat
Products:     Kcng1

Top Publications

  1. Salinas M, Duprat F, Heurteaux C, Hugnot J, Lazdunski M. New modulatory alpha subunits for mammalian Shab K+ channels. J Biol Chem. 1997;272:24371-9 pubmed
    ..The increasing number of modulatory subunits for Kv2.1 and Kv2.2 provides an amazingly new capacity of functional diversity. ..
  2. Drewe J, Verma S, Frech G, Joho R. Distinct spatial and temporal expression patterns of K+ channel mRNAs from different subfamilies. J Neurosci. 1992;12:538-48 pubmed
    ..One of the "brain-specific" K+ channels is first expressed after about 2 weeks of postnatal cerebellar development and remains at levels about 10-fold higher in the cerebellum than in the rest of the brain. ..
  3. Mederos y Schnitzler M, Rinné S, Skrobek L, Renigunta V, Schlichthörl G, Derst C, et al. Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4. J Biol Chem. 2009;284:4695-704 pubmed publisher
    ..1 is required for functional heteromerization with members of the Kv6 subfamily. We conclude from our findings that Kv2.1 and Kv6.x subunits have complementary T1 domains that control selective heteromerization. ..
  4. Post M, Kirsch G, Brown A. Kv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel current. FEBS Lett. 1996;399:177-82 pubmed
    ..1. Our results indicate that Kv channel subfamilies can form heteromultimeric channels and, for the first time, suggest a possible functional role for the Kv6 subfamily. ..