Gene Symbol: Itgad
Description: integrin subunit alpha D
Alias: Itgax, integrin alpha-D, integrin alpha X (Cd11c)
Species: rat
Products:     Itgad

Top Publications

  1. Shelley C, Teodoridis J, Park H, Farokhzad O, Bottinger E, Arnaout M. During differentiation of the monocytic cell line U937, Pur alpha mediates induction of the CD11c beta 2 integrin gene promoter. J Immunol. 2002;168:3887-93 pubmed
    ..Together, these increases in the functional activity of both Puralpha and Sp1 combine to induce CD11c expression. ..
  2. Hynes R. Integrins: bidirectional, allosteric signaling machines. Cell. 2002;110:673-87 pubmed
    ..Long-range conformational changes couple these functions via allosteric equilibria. ..
  3. Thomas A, Dunn T, Oort P, Grino M, Adams S. Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obese rodents and women. J Nutr. 2011;141:1172-80 pubmed publisher
  4. Wu H, Rodgers J, Perrard X, Perrard J, Prince J, Abe Y, et al. Deficiency of CD11b or CD11d results in reduced staphylococcal enterotoxin-induced T cell response and T cell phenotypic changes. J Immunol. 2004;173:297-306 pubmed
  5. Hurtado A, Marcillo A, Frydel B, Bunge M, Bramlett H, Dietrich W. Anti-CD11d monoclonal antibody treatment for rat spinal cord compression injury. Exp Neurol. 2012;233:606-11 pubmed publisher
  6. Tamatani T, Kotani M, Miyasaka M. Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. Eur J Immunol. 1991;21:627-33 pubmed
    ..Both WT.1 (anti-CD11a) and WT.3 (anti-CD18) apparently recognize a "low-affinity" as well as a "high-affinity" form of LFA-1 and do not discriminate between the two. ..
  7. Zhou C, Robertson J, Wu J, Bartkowiak T, Parker K, McMahon J, et al. Natural recovery from antiglomerular basement membrane glomerulonephritis is associated with glomeruli-infiltrating CD8?+CD11c+MHC class II+ cells. Am J Nephrol. 2011;34:519-28 pubmed publisher
    ..We investigated if GIL CD8?(+) cells were also associated with the recovery in LEW rats...