Gene Symbol: Hoxa10
Description: homeobox A10
Alias: homeobox protein Hox-A10
Varayoud J, Ramos J, Bosquiazzo V, Muñoz de Toro M, Luque E. Developmental exposure to Bisphenol a impairs the uterine response to ovarian steroids in the adult. Endocrinology. 2008;149:5848-60 pubmed publisher
..We investigated whether neonatal exposure to bisphenol A (BPA) alters Hoxa10 and Hoxa11 mRNA uterine expression shortly after treatment as well as in the adult...
Shen W, Montgomery J, Rozenfeld S, Moskow J, Lawrence H, Buchberg A, et al
. AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. Mol Cell Biol. 1997;17:6448-58 pubmed
..DNA binding complexes formed by Meis1 with Hox proteins dissociate much more slowly than DNA complexes with Meis1 alone, suggesting that Hox proteins stabilize the interactions of Meis1 proteins with their DNA targets. ..
Zhao Y, Potter S. Functional comparison of the Hoxa 4, Hoxa 10, and Hoxa 11 homeoboxes. Dev Biol. 2002;244:21-36 pubmed
..It is interesting that Hox homeoboxes are interchangeable in this process, but are functionally distinct in other aspects of development. ..
Wellik D, Capecchi M. Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton. Science. 2003;301:363-7 pubmed
..The redundancy among these paralogous family members is so great that this global aspect of Hox patterning is not apparent in mice that are mutant for five of the six paralogous alleles. ..
Bae N, Swanson M, Vassilev A, Howard B. Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10. J Biochem. 2004;135:695-700 pubmed
..Here we show for the first time that SIRT2 interacts with the homeobox transcription factor, HOXA10, which was identified in a two-hybrid screen...
Huang L, Pu Y, Hepps D, Danielpour D, Prins G. Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes. Endocrinology. 2007;148:1235-45 pubmed
..Expression levels of the three Hox13 genes and Hoxa10 were significantly higher in the adult VP compared with the neonatal developing VP suggesting an important role ..
Bei L, Huang W, Wang H, Shah C, Horvath E, Eklund E. HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cells. J Biol Chem. 2011;286:19047-64 pubmed publisher
b>HoxA10 is a homeodomain transcription factor that influences a number of developmental processes, including hematopoiesis...
Raines A, Adam M, Magella B, Meyer S, Grimes H, Dey S, et al
. Recombineering-based dissection of flanking and paralogous Hox gene functions in mouse reproductive tracts. Development. 2013;140:2942-52 pubmed publisher
..the use of a novel recombineering strategy to introduce simultaneous frameshift mutations into the flanking Hoxa9, Hoxa10 and Hoxa11 genes, as well as their paralogs on the HoxD cluster...