Hgf

Summary

Gene Symbol: Hgf
Description: hepatocyte growth factor
Alias: HPTA, hepatocyte growth factor, hepatopoeitin-A, hepatopoietin-A, scatter factor
Species: rat
Products:     Hgf

Top Publications

  1. Ono M, Sawa Y, Mizuno S, Fukushima N, Ichikawa H, Bessho K, et al. Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats. Circulation. 2004;110:2896-902 pubmed
    ..a rat model of advanced pulmonary vascular disease produced by injecting monocrotaline, we show that hepatocyte growth factor (HGF) targets pulmonary arterioles and blocks the progression of PH...
  2. Wang P, Li S, Xiao X, Jia X, Jiao X, Guo X, et al. High myopia is not associated with the SNPs in the TGIF, lumican, TGFB1, and HGF genes. Invest Ophthalmol Vis Sci. 2009;50:1546-51 pubmed publisher
    Four single-nucleotide polymorphisms (SNPs) in the TGIF, lumican, TGFB1, and HGF genes have been declared to be associated with high myopia in Chinese living in southeast China, but none of them has been confirmed by additional studies...
  3. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, et al. Molecular cloning and expression of human hepatocyte growth factor. Nature. 1989;342:440-3 pubmed
    b>Hepatocyte growth factor (HGF) is the most potent mitogen for mature parenchymal hepatocytes in primary culture, and seems to be a hepatotrophic factor that acts as a trigger for liver regeneration after partial hepatectomy and liver ..
  4. Han W, Yap M, Wang J, Yip S. Family-based association analysis of hepatocyte growth factor (HGF) gene polymorphisms in high myopia. Invest Ophthalmol Vis Sci. 2006;47:2291-9 pubmed
    To investigate the association of high myopia with polymorphisms in the hepatocyte growth factor (HGF) gene, a potential candidate for myopia development...
  5. Yoshimura R, Watanabe Y, Kasai S, Wada S, Ohyama A, Hase T, et al. Hepatocyte growth factor (HGF) as a rapid diagnostic marker and its potential in the prevention of acute renal rejection. Transpl Int. 2002;15:156-62 pubmed
    Several investigators have reported that hepatocyte growth factor (HGF) may be related to the protection or reconstruction of the kidney during acute renal rejection...
  6. Kitamura K, Iwanami A, Nakamura M, Yamane J, Watanabe K, Suzuki Y, et al. Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury. J Neurosci Res. 2007;85:2332-42 pubmed
    ..b>Hepatocyte growth factor (HGF), which was identified as a potent mitogen for mature hepatocytes and a mediator of inflammatory ..
  7. Homsi E, Janino P, Amano M, Saraiva Camara N. Endogenous hepatocyte growth factor attenuates inflammatory response in glycerol-induced acute kidney injury. Am J Nephrol. 2009;29:283-91 pubmed publisher
    b>Hepatocyte growth factor (HGF) is overexpressed after acute kidney injury (AKI). The aim of this study was to evaluate the role of endogenous HGF in the progression of the inflammatory response in glycerol-induced AKI (Gly-AKI) in rats...
  8. Shukla M, Rose J, Ray R, Lathrop K, Ray A, Ray P. Hepatocyte growth factor inhibits epithelial to myofibroblast transition in lung cells via Smad7. Am J Respir Cell Mol Biol. 2009;40:643-53 pubmed publisher
    ..b>Hepatocyte growth factor (HGF) inhibits progression of bleomycin-induced pulmonary fibrosis in mice...
  9. Yanovitch T, Li Y, Metlapally R, Abbott D, Viet K, Young T. Hepatocyte growth factor and myopia: genetic association analyses in a Caucasian population. Mol Vis. 2009;15:1028-35 pubmed
    b>Hepatocyte growth factor (HGF) and hepatocyte growth factor receptor (C-MET) genes have previously been reported to be associated with myopia in Asian family-based and case-control association studies, respectively...

More Information

Publications62

  1. Kuroiwa T, Kakishita E, Hamano T, Kataoka Y, Seto Y, Iwata N, et al. Hepatocyte growth factor ameliorates acute graft-versus-host disease and promotes hematopoietic function. J Clin Invest. 2001;107:1365-73 pubmed
    ..b>Hepatocyte growth factor (HGF), originally identified and cloned as a potent mitogen for hepatocytes, induces mitogenic and ..
  2. Wu M, Yokozeki H, Takagawa S, Yamamoto T, Satoh T, Kaneda Y, et al. Hepatocyte growth factor both prevents and ameliorates the symptoms of dermal sclerosis in a mouse model of scleroderma. Gene Ther. 2004;11:170-80 pubmed
    ..working with a bleomycin(BLM)-induced scleroderma model mice, we performed two transfections of human hepatocyte growth factor (HGF) cDNA into the skeletal muscle and showed that this treatment not only helped to prevent the dermal ..
  3. Yuasa I, Tsukuda K, Hirai R, Ota T, Murakami M, Naito M, et al. Effects of adenoviral-mediated hepatocyte growth factor on liver regeneration after massive hepatectomy in rats. Acta Med Okayama. 2007;61:81-8 pubmed
    ..This study was attempted to promote liver regeneration using hepatocyte growth factor (HGF) gene transfection by venous-administered adenovirus and to improve the survival of rats after ..
  4. Catizone A, Ricci G, Tufano M, Perfetto B, Canipari R, Galdieri M. Hepatocyte growth factor (HGF) modulates Leydig cell extracellular matrix components. J Androl. 2010;31:306-13 pubmed publisher
    b>Hepatocyte growth factor (HGF) is a pleiotropic factor that plays multiple roles during mammalian development...
  5. Higuchi T, Orita T, Katsuya K, Yamasaki Y, Akiyama K, Li H, et al. MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met. Mol Cell Biol. 2004;24:7456-68 pubmed
    ..docking site of Met without ligand activation, preventing Grb2 recruitment to Met and thus attenuating hepatocyte growth factor (HGF)-induced transient extracellular signal-regulated kinase-1 and -2 activation...
  6. Guo Y, Su L, Li Y, Guo N, Xie L, Zhang D, et al. The synergistic therapeutic effect of hepatocyte growth factor and granulocyte colony-stimulating factor on pulmonary hypertension in rats. Heart Vessels. 2014;29:520-31 pubmed publisher
    ..to investigate whether the transplantation of bone marrow mesenchymal stem cells (MSCs) overexpressing hepatocyte growth factor (HGF), alone or in combination with granulocyte colony-stimulating factor (G-CSF), attenuates the ..
  7. Timmapuri S, Otterburn D, Arafat H, Schwartz M. Hepatocyte growth factor increases glucagon immunoreactivity in jejunal cells during intestinal adaptation. J Pediatr Surg. 2006;41:150-4; discussion 150-4 pubmed
    The administration of hepatocyte growth factor (HGF) during intestinal adaptation is known to enhance intestinal adaptation. Glucagon has also been implicated as a potential mediator of intestinal adaptation...
  8. Takahashi T, Friedmacher F, Zimmer J, Puri P. Decreased expression of hepatocyte growth factor in the nitrofen model of congenital diaphragmatic hernia. Pediatr Surg Int. 2016;32:967-73 pubmed publisher
    ..b>Hepatocyte growth factor (Hgf), which is secreted in PPFs, plays a crucial role in the formation of the muscular diaphragmatic ..
  9. Okajima A, Miyazawa K, Kitamura N. Primary structure of rat hepatocyte growth factor and induction of its mRNA during liver regeneration following hepatic injury. Eur J Biochem. 1990;193:375-81 pubmed
    Overlapping cDNA clones for rat hepatocyte growth factor (rHGF) were isolated by cross-hybridization with the cloned cDNA for human hepatocyte growth factor (hHGF) and the nucleotide sequence of the cDNA was determined...
  10. Seedorf G, Metoxen A, ROCK R, Markham N, Ryan S, Vu T, et al. Hepatocyte growth factor as a downstream mediator of vascular endothelial growth factor-dependent preservation of growth in the developing lung. Am J Physiol Lung Cell Mol Physiol. 2016;310:L1098-110 pubmed publisher
    ..may be mediated through its downstream effects on both endothelial nitric oxide synthase (eNOS) and hepatocyte growth factor (HGF) activity, and that, in the absence of eNOS, trophic effects of VEGF would be mediated through HGF ..
  11. Salom D, Diaz Llopis M, Quijada A, Garcia Delpech S, Udaondo P, Romero F, et al. Aqueous humor levels of hepatocyte growth factor in retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2010;51:3157-61 pubmed publisher
    To determine the level of hepatocyte growth factor (HGF) in the aqueous humor of patients with retinitis pigmentosa (RP). This was a prospective, comparative control study...
  12. Moreno E, Meneu J, Calvo J, Perez B, Sesma A, Manrique A, et al. Modulation of hepatocyte growth factor plasma levels in relation to the dose of exogenous heparin administered: an experimental study in rats. Transplant Proc. 2005;37:3943-7 pubmed
    ..We sought to determine the impact of heparin on m-hepatocyte growth factor (HGF) plasma concentrations...
  13. Corpechot C, Barbu V, Wendum D, Chignard N, Housset C, Poupon R, et al. Hepatocyte growth factor and c-Met inhibition by hepatic cell hypoxia: a potential mechanism for liver regeneration failure in experimental cirrhosis. Am J Pathol. 2002;160:613-20 pubmed
    ..b>Hepatocyte growth factor (HGF) and c-Met expressions were determined by reverse transcriptase-polymerase chain reaction, Northern ..
  14. Evans I, Yamaji M, Britton G, Pellet Many C, Lockie C, Zachary I, et al. Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells. Mol Cell Biol. 2011;31:1174-85 pubmed publisher
    ..Here we report that p130(Cas) tyrosine phosphorylation is stimulated by hepatocyte growth factor and platelet-derived growth factor in U87MG glioma cells and VEGF in endothelial cells and is dependent ..
  15. Paranjpe S, Bowen W, Bell A, Nejak Bowen K, Luo J, Michalopoulos G. Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference. Hepatology. 2007;45:1471-7 pubmed
    b>Hepatocyte growth factor (HGF) and its receptor c-Met are involved in liver regeneration...
  16. Suzuki T, Kanai Y, Hara T, Sasaki J, Sasaki T, Kohara M, et al. Crucial role of the small GTPase ARF6 in hepatic cord formation during liver development. Mol Cell Biol. 2006;26:6149-56 pubmed
    ..Consistent with this observation, the ability of hepatocyte growth factor/scatter factor (HGF) to induce hepatic cord-like structures from ARF6-/- fetal hepatocytes cultured in ..
  17. Zhu G, Huang L, Song M, Yu Z, Wu X, Zhao X, et al. Over-expression of hepatocyte growth factor in smooth muscle cells regulates endothelial progenitor cells differentiation, migration and proliferation. Int J Cardiol. 2010;138:70-80 pubmed publisher
    Endothelial repair is one of key events after vascular injury. The mechanisms by which hepatocyte growth factor (HGF) and endothelial progenitor cells (EPCs) may be responsible for re-endothelialization of injured blood vessel wall are ..
  18. Zuo C, Qiu H, Xie X, Deng Y, Fan J. [Effect of Astragalus mongholicus on expression of hepatocyte growth factor in SD rats with unilateral ureteral obstruction]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2009;40:100-5 pubmed
    To study the effect of Astragalus mongholicus (AM) on the expression of hepatocyte growth factor (HGF) in SD rats with unilateral ureteral obstruction (UUO) and to elucidate the mechanisms underlying the renoprotective effects of AM...
  19. Lionetti V, Cantoni S, Cavallini C, Bianchi F, Valente S, Frascari I, et al. Hyaluronan mixed esters of butyric and retinoic acid affording myocardial survival and repair without stem cell transplantation. J Biol Chem. 2010;285:9949-61 pubmed publisher
    ..and Stro-1 stem cells, HBR enhanced the transcription of vascular endothelial growth factor, hepatocyte growth factor, kdr, akt, and pim-1...
  20. Castano R, Bosse Y, Endam L, Filali Mouhim A, Desrosiers M. c-MET pathway involvement in chronic rhinosinusitis: a genetic association analysis. Otolaryngol Head Neck Surg. 2010;142:665-71.e1-2 pubmed publisher
    The c-MET receptor and its ligand hepatocyte growth factor (HGF) has been shown to be overexpressed in tissue from chronic rhinosinusitis (CRS) patients with nasal polyps compared with that from controls...
  21. Naeem A, Abbas L, Guthrie S. Comparison of the effects of HGF, BDNF, CT-1, CNTF, and the branchial arches on the growth of embryonic cranial motor neurons. J Neurobiol. 2002;51:101-14 pubmed
    ..We have shown previously that the branchial arches and hepatocyte growth factor (HGF) are growth-promoting and chemoattractant for young embryonic cranial motor axons...
  22. Gregorini M, Bosio F, Rocca C, Corradetti V, Valsania T, Pattonieri E, et al. Mesenchymal stromal cells reset the scatter factor system and cytokine network in experimental kidney transplantation. BMC Immunol. 2014;15:44 pubmed publisher
    ..e. Hepatocyte Growth Factor (HGF), Macrophage Stimulating Protein (MSP) and their receptors Met and RON, respectively...
  23. Saghizadeh M, Kramerov A, Tajbakhsh J, Aoki A, Wang C, Chai N, et al. Proteinase and growth factor alterations revealed by gene microarray analysis of human diabetic corneas. Invest Ophthalmol Vis Sci. 2005;46:3604-15 pubmed
    ..Expression of cathepsin F and hepatocyte growth factor (HGF) genes was increased in ex vivo and organ-cultured DR corneas compared with normal corneas...
  24. Li Y, Spataro B, Yang J, Dai C, Liu Y. 1,25-dihydroxyvitamin D inhibits renal interstitial myofibroblast activation by inducing hepatocyte growth factor expression. Kidney Int. 2005;68:1500-10 pubmed
    ..Expression of alpha-SMA, collagen I, thrombospondin-1, and hepatocyte growth factor (HGF) was assessed by reverse transcription-polymerase chain reaction (RT-PCR), Western blot, and ..
  25. Hayashi Y, Kawazoe Y, Sakamoto T, Ojima M, Wang W, Takazawa T, et al. Adenoviral gene transfer of hepatocyte growth factor prevents death of injured adult motoneurons after peripheral nerve avulsion. Brain Res. 2006;1111:187-95 pubmed
    b>Hepatocyte growth factor (HGF) exhibits strong neurotrophic activities on motoneurons both in vitro and in vivo...
  26. Rao U, Sonmez Alpan E, Michalopoulos G. Hepatocyte growth factor and c-MET in benign and malignant peripheral nerve sheath tumors. Hum Pathol. 1997;28:1066-70 pubmed
    b>Hepatocyte growth factor (HGF), secreted by mesenchymal cells, has pleiotropic biological activities on several cell types...
  27. Colombo E, Menicucci G, McGuire P, Das A. Hepatocyte growth factor/scatter factor promotes retinal angiogenesis through increased urokinase expression. Invest Ophthalmol Vis Sci. 2007;48:1793-800 pubmed
    The purpose of this study was to determine the role of hepatocyte growth factor (HGF) and c-Met in the initiation and development of retinal neovascularization and to determine whether inhibition of this system can suppress the extent of ..
  28. Sun W, Funakoshi H, Nakamura T. Localization and functional role of hepatocyte growth factor (HGF) and its receptor c-met in the rat developing cerebral cortex. Brain Res Mol Brain Res. 2002;103:36-48 pubmed
    ..b>Hepatocyte growth factor (HGF) is a pleiotrophic cytokine, which plays important roles in the organogenesis and regeneration of ..
  29. Su Y, Li H, Zhang J, Xiu R. Down-regulation of hepatocyte growth factor mRNA in rat cardiac myocytes under hypoxia mimicked by cobalt chloride. Clin Hemorheol Microcirc. 2006;34:201-6 pubmed
    ..angiogenic factors were up-regulated by hypoxia, but as a strong angiogenic and antiapoptotic factor, hepatocyte growth factor (HGF) was down-regulated by hypoxia...
  30. Ono K, Kamiya S, Akatsu T, Nakamura C, Li M, Amizuka N, et al. Involvement of hepatocyte growth factor in the development of bone metastasis of a mouse mammary cancer cell line, BALB/c-MC. Bone. 2006;39:27-34 pubmed
    ..After tumors metastasize to bone, they stimulate osteoclastogenesis and expand in the bone tissue. Hepatocyte growth factor (HGF), which was originally identified as a potent mitogen for hepatocytes, promotes tumor growth, ..
  31. Dong L, Jiang Y, Liu Y, Cui S, Xia C, Qu C, et al. The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2. Sci Rep. 2015;5:8713 pubmed publisher
    ..After mesenchymal stem cells were infused, host secretions of hepatocyte growth factor (HGF) and prostaglandin E2 (PGE2) were elevated compared with those of the controls...
  32. Katoh H, Shimada T, Inoue S, Takahashi N, Shimizu H, Ohta Y, et al. Reduced high serum hepatocyte growth factor levels after successful cardioversion in patients with atrial fibrillation. Clin Exp Pharmacol Physiol. 2004;31:145-51 pubmed
    1. Serum hepatocyte growth factor (HGF) is considered to be a potent marker of vascular endothelial injury...
  33. Naim R, Riedel F, Gotte K, Bran G, Sadick H, Gossler U, et al. Co-expression of different angiogenic factors in external auditory canal cholesteatoma. Acta Otolaryngol. 2004;124:563-8 pubmed
    ..of 13 investigated EACC tissue samples and normal control tissue were immunostained for angiogenic hepatocyte growth factor (HGF)/scatter factor (SF), its c-Met receptor and vascular endothelial growth factor (VEGF) using a ..
  34. Aparicio I, Garcia Marin L, Andreolotti A, Bodega G, Jensen R, Bragado M. Hepatocyte growth factor activates several transduction pathways in rat pancreatic acini. Biochim Biophys Acta. 2003;1643:37-46 pubmed
    The receptor of hepatocyte growth factor (HGF), c-met induces different physiological responses in several cell types. Little is known about the role of HGF in exocrine pancreas...
  35. Rehman J, Considine R, Bovenkerk J, Li J, Slavens C, Jones R, et al. Obesity is associated with increased levels of circulating hepatocyte growth factor. J Am Coll Cardiol. 2003;41:1408-13 pubmed
    This study evaluated whether obesity in humans was associated with an increase in circulating hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF) levels...
  36. Shen Z, Yang Z, Gao Y, Li J, Chen H, Liu C, et al. The kringle 1 domain of hepatocyte growth factor has antiangiogenic and antitumor cell effects on hepatocellular carcinoma. Cancer Res. 2008;68:404-14 pubmed publisher
    The kringle 1 domain of human hepatocyte growth factor (HGFK1) was previously shown to inhibit bovine aortic endothelial cell proliferation, suggesting that it might be an antiangiogenic molecule...
  37. Price J, Kovach S, Johnson T, Koniaris L, Cahill P, Sitzmann J, et al. Insulin-like growth factor I is a comitogen for hepatocyte growth factor in a rat model of hepatocellular carcinoma. Hepatology. 2002;36:1089-97 pubmed
    b>Hepatocyte growth factor-scatter factor (HGF-SF) is a potent hepatic mitogen yet inhibits hepatocellular carcinoma (HCC) cell growth in vitro...
  38. Soldati C, Biagioni S, Poiana G, Augusti Tocco G. beta-Catenin and actin reorganization in HGF/SF response of ST14A cells. J Neurosci Res. 2008;86:1044-52 pubmed
    b>Hepatocyte growth factor/scatter factor (HGF/SF) is a pleiotropic factor that activates proliferation, differentiation, and migration of various cell types...
  39. Machide M, Hashigasako A, Matsumoto K, Nakamura T. Contact inhibition of hepatocyte growth regulated by functional association of the c-Met/hepatocyte growth factor receptor and LAR protein-tyrosine phosphatase. J Biol Chem. 2006;281:8765-72 pubmed
    ..hepatocytes, we investigated the mechanisms of contact inhibition that decrease the mitogenic activity of hepatocyte growth factor (HGF), focusing on the regulation of c-Met/HGF-receptor activation...
  40. Ohya W, Funakoshi H, Kurosawa T, Nakamura T. Hepatocyte growth factor (HGF) promotes oligodendrocyte progenitor cell proliferation and inhibits its differentiation during postnatal development in the rat. Brain Res. 2007;1147:51-65 pubmed
    b>Hepatocyte growth factor (HGF) was initially cloned as a mitogen for hepatocytes and has been identified as a neurotrophic factor for a variety of neurons...
  41. Kaga T, Kawano H, Sakaguchi M, Nakazawa T, Taniyama Y, Morishita R. Hepatocyte growth factor stimulated angiogenesis without inflammation: differential actions between hepatocyte growth factor, vascular endothelial growth factor and basic fibroblast growth factor. Vascul Pharmacol. 2012;57:3-9 pubmed publisher
    Based on the potent angiogenic effects of hepatocyte growth factor (HGF), therapeutic angiogenesis using human HGF plasmid DNA increased tissue perfusion and reduced symptoms in patients with critical limb ischemia (CLI) in randomized ..
  42. Hu S, Li J, Xu X, Liu A, He H, Xu J, et al. The hepatocyte growth factor-expressing character is required for mesenchymal stem cells to protect the lung injured by lipopolysaccharide in vivo. Stem Cell Res Ther. 2016;7:66 pubmed publisher
    ..stem cells (MSC) improved the permeability of human lung microvascular endothelial cells by secreting hepatocyte growth factor (HGF) in vitro...
  43. Hashimoto N, Yamanaka H, Fukuoka T, Obata K, Mashimo T, Noguchi K. Expression of hepatocyte growth factor in primary sensory neurons of adult rats. Brain Res Mol Brain Res. 2001;97:83-8 pubmed
    We examined the expression of hepatocyte growth factor (HGF) mRNA and its receptor, c-met mRNA, in the dorsal root ganglia (DRG) and spinal cord of naive adult rats using in situ hybridization histochemistry (ISHH) and the reverse ..
  44. Chu S, Feng D, Ma Y, Zhang H, Zhu Z, Li Z, et al. Expression of HGF and VEGF in the cerebral tissue of adult rats with chronic hydrocephalus after subarachnoid hemorrhage. Mol Med Rep. 2011;4:785-91 pubmed publisher
    The hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF) are important cytokines with modulatory actions in the nervous system...
  45. Suzuki S, Yamanouchi K, Soeta C, Katakai Y, Harada R, Naito K, et al. Skeletal muscle injury induces hepatocyte growth factor expression in spleen. Biochem Biophys Res Commun. 2002;292:709-14 pubmed
    b>Hepatocyte growth factor (HGF) is present in skeletal muscle and facilitates skeletal muscle regeneration by activating quiescent satellite cells and stimulating their proliferation...
  46. Shang J, Deguchi K, Yamashita T, Ohta Y, Zhang H, Morimoto N, et al. Antiapoptotic and antiautophagic effects of glial cell line-derived neurotrophic factor and hepatocyte growth factor after transient middle cerebral artery occlusion in rats. J Neurosci Res. 2010;88:2197-206 pubmed publisher
    Glial cell line-derived neurotrophic factor (GDNF) and hepatocyte growth factor (HGF) are strong neurotrophic factors, which function as antiapoptotic factors...
  47. Nishimura M, Ushiyama M, Nanbu A, Ohtsuka K, Takahashi H, Yoshimura M. Serum hepatocyte growth factor as a possible indicator of arteriosclerosis. J Hypertens. 1997;15:1137-42 pubmed
    To investigate the possible involvement of hepatocyte growth factor in arteriosclerotic lesions, by studying the relationship between serum concentrations of hepatocyte growth factor and grades of retinal arteriosclerosis...
  48. Yuan L, Lou W, Sang J. [Expression and significances of FSCN1 and HGF in nasal inverted papilloma]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012;26:339-42 pubmed
    To study the expressions of FSCN1 and HGF in nasal inverted papilloma (NIP) and explore their role in occurrence and development of this disease...
  49. Cecchi F, Pajalunga D, Fowler C, Uren A, Rabe D, Peruzzi B, et al. Targeted disruption of heparan sulfate interaction with hepatocyte and vascular endothelial growth factors blocks normal and oncogenic signaling. Cancer Cell. 2012;22:250-62 pubmed publisher
    b>Hepatocyte growth factor (HGF) and vascular endothelial cell growth factor (VEGF) regulate normal development and homeostasis and drive disease progression in many forms of cancer...
  50. Tönges L, Ostendorf T, Lamballe F, Genestine M, Dono R, Koch J, et al. Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo. J Neurochem. 2011;117:892-903 pubmed publisher
    b>Hepatocyte growth factor (HGF) is known to promote the survival and foster neuritic outgrowth of different subpopulations of CNS neurons during development...
  51. Zhou N, Fu Y, Wang Y, Chen P, Meng H, Guo S, et al. p27 kip1 haplo-insufficiency improves cardiac function in early-stages of myocardial infarction by protecting myocardium and increasing angiogenesis by promoting IKK activation. Sci Rep. 2014;4:5978 pubmed publisher
    ..In this study, we investigated the relationships between p27, vascular endothelial growth factor/hepatocyte growth factor (VEGF/HGF) and NF-?B in post-MI cardiac function repair both in vivo and in the hypoxia/ischemia-induced ..
  52. Pediaditakis P, Monga S, Mars W, Michalopoulos G. Differential mitogenic effects of single chain hepatocyte growth factor (HGF)/scatter factor and HGF/NK1 following cleavage by factor Xa. J Biol Chem. 2002;277:14109-15 pubmed
    b>Hepatocyte growth factor/scatter factor (HGF/SF) is a multifunctional cytokine that is involved in many normal as well as pathological conditions...
  53. Watanabe K, Fukuda H, Sueda S, Funada J, Kitakaze M, Sekiya M. Metabolism of hepatocyte growth factor in the heart in patients with coronary artery disease: implication for coronary arteriosclerosis. Cardiovasc Drugs Ther. 2001;15:147-53 pubmed
    ..We examined the levels of hepatocyte growth factor (HGF) in the coronary circulation and its correlation with the severity of arteriosclerosis in patients ..