Genomes and Genes
Gene Symbol: Glb1
Description: galactosidase, beta 1
- Rajashree S, Puvanakrishnan R. Alterations in certain lysosomal glycohydrolases and cathepsins in rats on dexamethasone administration. Mol Cell Biochem. 1996;154:165-70 pubmed..Thus, it could be seen that dexamethasone alters the pattern of glycohydrolases and cathepsins, which are involved in protein degradation. ..
- Sleat D, Sohar I, Lackland H, Majercak J, Lobel P. Rat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosis. J Biol Chem. 1996;271:19191-8 pubmed..This finding raises important questions about the cellular location and function of palmitoyl protein thioesterase, mutations in which result in the neurodegenerative disorder, infantile neuronal ceroid lipofuscinosis. ..
- Douglas T, Kimmel K, Dawson P. Genetically controlled variation of "acid" beta-galactosidase detected in Rattus norvegicus by isoelectric focusing. Genetics. 1982;100:455-73 pubmed..The beta-galactosidase present in the bands used for Glb-1 typing resembles human GM1 gangliosidase (GLB1) with respect to pH optimum, substrate specificity, and susceptibility to inhibition by PMB...
- Leeper L, Henning S. Hormonal control of postnatal development of ileal neuraminidase and acid beta-galactosidase. Biol Neonate. 1983;44:28-35 pubmed..It is likely that glucocorticoids act as the primary cue in the maturation of these enzymes, but with T4 interaction necessary for the normal pattern to be elicited. ..
- Felton J, Meisler M, Paigen K. A locus determining beta-galactosidase activity in the mouse. J Biol Chem. 1974;249:3267-72 pubmed
- Majumder G, Turkington R. Acrosomal and lysosomal isoenzymes of beta-galactosidase and N-acetyl-beta-glucosaminidase in rat testis. Biochemistry. 1974;13:2857-64 pubmed
- Gibb S, Håkansson E, Lundin L, Shire J. Reduced pigmentation (rp), a new coat colour gene with effects on kidney lysosomal glycosidases in the mouse. Genet Res. 1981;37:95-103 pubmed