Gfap

Summary

Gene Symbol: Gfap
Description: glial fibrillary acidic protein
Alias: glial fibrillary acidic protein, glial fibrillary acidic protein alpha, glial fibrillary acidic protein delta, intermediate filament
Species: rat
Products:     Gfap

Top Publications

  1. Pecchi E, Dallaporta M, Charrier C, Pio J, Jean A, Moyse E, et al. Glial fibrillary acidic protein (GFAP)-positive radial-like cells are present in the vicinity of proliferative progenitors in the nucleus tractus solitarius of adult rat. J Comp Neurol. 2007;501:353-68 pubmed
    ..We report a strikingly high density of glial fibrillary acidic protein (GFAP) immunoreactive cells in the NTS and the DMNX compared to other brainstem structures...
  2. Singh R, Nielsen A, Johansen M, Jørgensen A. Genetic polymorphism and sequence evolution of an alternatively spliced exon of the glial fibrillary acidic protein gene, GFAP. Genomics. 2003;82:185-93 pubmed
    Isoform GFAPepsilon of the human cytoskeletal protein GFAP carries, as the result of alternative splicing of exon 7a of GFAP, a novel 42-amino-acid-long C-terminal region with binding capacity for the presenilin proteins...
  3. McCall M, Gregg R, Behringer R, Brenner M, Delaney C, Galbreath E, et al. Targeted deletion in astrocyte intermediate filament (Gfap) alters neuronal physiology. Proc Natl Acad Sci U S A. 1996;93:6361-6 pubmed
    b>Glial fibrillary acidic protein (GFAP) is a member of the family of intermediate filament structural proteins and is found predominantly in astrocytes of the central nervous system (CNS)...
  4. Nichols N, Osterburg H, Masters J, Millar S, Finch C. Messenger RNA for glial fibrillary acidic protein is decreased in rat brain following acute and chronic corticosterone treatment. Brain Res Mol Brain Res. 1990;7:1-7 pubmed
    ..By hybrid selection and in vitro translation, the 50 kDa polypeptide is identified as glial fibrillary acidic protein (GFAP). Hippocampal GFAP mRNA (2...
  5. Salmaso N, Woodside B. Upregulation of astrocytic basic fibroblast growth factor in the cingulate cortex of lactating rats: time course and role of suckling stimulation. Horm Behav. 2006;50:448-53 pubmed
    Previous work from our laboratory has shown that there is a much higher level of bFGF and GFAP immunoreactivity in area 2 of the cingulate cortex (Cg2) of rats on day 16 of lactation than in cycling or late pregnant females...
  6. Herrera F, Chen Q, Schubert D. Synergistic effect of retinoic acid and cytokines on the regulation of glial fibrillary acidic protein expression. J Biol Chem. 2010;285:38915-22 pubmed publisher
    b>Glial fibrillary acidic protein (GFAP) is the main astroglial marker during astrogliogenesis, but it is also expressed in other cell types, including neural stem cells and old neurons...
  7. Lally B, Albrecht P, Levison S, Salm A. Divergent glial fibrillary acidic protein and its mRNA in the activated supraoptic nucleus. Neurosci Lett. 2005;380:295-9 pubmed
    Previous studies have shown decreased immunoreactive glial fibrillary acidic protein (GFAP) in the supraoptic nucleus (SON) when magnocellular neuroendocrine cells (MNCs) are activated by lactation or dehydration...
  8. Xu J, Sun D, Liu X, Liu H, Hua X, Chen X. [Effect of chondroitinase ABC on growth associate protein 43 and glial fibrillary acidic protein after spinal cord injury in rats]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2010;24:1212-6 pubmed
    ..effect of chondroitinase ABC (ChABC) on the expression of growth associated protein 43 (GAP-43) and glial fibrillary acidic protein (GFAP) after spinal cord injury (SCI) in rats...
  9. Gerics B, Szalay F, Hajos F. Glial fibrillary acidic protein immunoreactivity in the rat suprachiasmatic nucleus: circadian changes and their seasonal dependence. J Anat. 2006;209:231-7 pubmed
    ..SCN) of the hypothalamus, was studied in intact male rats to determine its immunoreactivity to glial fibrillary acidic protein (GFAP), a specific marker of astrocytes...

More Information

Publications62

  1. Nagatani M, Yamakawa S, Saito T, Ando R, Hoshiya T, Tamura K, et al. GFAP-positive neoplastic astrocytes in spontaneous oligodendrogliomas and mixed gliomas of rats. Toxicol Pathol. 2013;41:653-61 pubmed publisher
    It is generally said that neoplastic cells are immunohistochemically negative for glial fibrillary acidic protein (GFAP) in rat spontaneous astrocytomas, and there are no reports describing the existence of GFAP-positive neoplastic ..
  2. Fukami S, Watanabe K, Iwata N, Haraoka J, Lu B, Gerard N, et al. Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology. Neurosci Res. 2002;43:39-56 pubmed
  3. Kuramochi Y, Takagi Sakuma M, Kitahara M, Emori R, Asaba Y, Sakaguchi R, et al. Characterization of mouse homolog of brain acyl-CoA hydrolase: molecular cloning and neuronal localization. Brain Res Mol Brain Res. 2002;98:81-92 pubmed
    ..These findings will contribute to the functional analysis of the BACH gene using mice including genetic studies. ..
  4. Zorkina Y, Yusubalieva G, Koshkin F, Chamorsov A, Kistenev A, Gorlachev G, et al. Expression of VEGF, GFAP, and BDNF genes in the brain of rats after fractionated γ-irradiation according to different protocols. Bull Exp Biol Med. 2014;157:501-5 pubmed publisher
    The expression of VEGF, GFAP, and BDNF genes in the nervous tissue changed on weeks 4, 8, and 12 after fractionated irradiation of the brain according to different protocols in a fixed total dose of 36 Gy...
  5. Bloancă V, Ceauşu A, Jitariu A, Barmayoun A, Moş R, Crăiniceanu Z, et al. Adipose Tissue Graft Improves Early but not Late Stages of Nerve Regeneration. In Vivo. 2017;31:649-655 pubmed
    ..Nerve biopsies were collected and immunohistochemical procedures were performed for glial fibrillary acidic protein (GFAP) and for neurofilament-associated protein(NFAP)...
  6. Roymans D, Willems R, Vissenberg K, De Jonghe C, Grobben B, Claes P, et al. Nucleoside diphosphate kinase beta (Nm23-R1/NDPKbeta) is associated with intermediate filaments and becomes upregulated upon cAMP-induced differentiation of rat C6 glioma. Exp Cell Res. 2000;261:127-38 pubmed
    ..colocalized and coimmunoprecipitated with vimentin in nondifferentiated cells, both isoforms were associated with GFAP in differentiated cells...
  7. Huang X, Glushakova O, Mondello S, Van K, Hayes R, Lyeth B. Acute Temporal Profiles of Serum Levels of UCH-L1 and GFAP and Relationships to Neuronal and Astroglial Pathology following Traumatic Brain Injury in Rats. J Neurotrauma. 2015;32:1179-89 pubmed publisher
    ..samples were analyzed for neuronal (ubiquitin carboxy-terminal hydrolase L1 [UCH-L1]) and astroglial (glial fibrillary acidic protein [GFAP]) protein levels using enzyme-linked immunosorbent assay...
  8. Gosselin R, Gibney S, O MALLEY D, Dinan T, Cryan J. Region specific decrease in glial fibrillary acidic protein immunoreactivity in the brain of a rat model of depression. Neuroscience. 2009;159:915-25 pubmed publisher
    ..In the present study, we investigated the expression of the astrocytic markers glial fibrillary acidic protein (GFAP) in various brain regions in WKY rats in comparison to Sprague-Dawley rats...
  9. Menet V, Gimenez y Ribotta M, Chauvet N, Drian M, Lannoy J, Colucci Guyon E, et al. Inactivation of the glial fibrillary acidic protein gene, but not that of vimentin, improves neuronal survival and neurite growth by modifying adhesion molecule expression. J Neurosci. 2001;21:6147-58 pubmed
    ..In mature differentiated astrocytes, vimentin is replaced by the IF protein glial fibrillary acidic protein (GFAP)...
  10. Gohara T, Ishida K, Nakakimura K, Yoshida M, Fukuda S, Matsumoto M, et al. Temporal profiles of aquaporin 4 expression and astrocyte response in the process of brain damage in fat embolism model in rats. J Anesth. 2010;24:225-33 pubmed publisher
    ..0-5 = no deficit-dead), brain water content, histopathology, and immunohistochemistry for AQP4 and glial fibrillary acidic protein (GFAP) were evaluated at 2 h (2 h group, n = 12), 24 h (24 h group, n = 12), and 72 h (72 h group, n =..
  11. Triolo D, Dina G, Lorenzetti I, Malaguti M, Morana P, Del Carro U, et al. Loss of glial fibrillary acidic protein (GFAP) impairs Schwann cell proliferation and delays nerve regeneration after damage. J Cell Sci. 2006;119:3981-93 pubmed
    ..We investigated whether peripheral nerve regeneration is perturbed in mice that lack glial fibrillary acidic protein (GFAP), a Schwann-cell-specific cytoskeleton constituent upregulated after damage...
  12. Arimoto J, Wong A, Rozovsky I, Lin S, Morgan T, Finch C. Age increase of estrogen receptor-? (ER?) in cortical astrocytes impairs neurotrophic support in male and female rats. Endocrinology. 2013;154:2101-13 pubmed publisher
    ..Because elevated expression of astrocyte glial fibrillary acidic protein (GFAP) is associated with impaired neurotrophic activity and because the GFAP promoter responds to ER?..
  13. Cebolla B, Vallejo M. Nuclear factor-I regulates glial fibrillary acidic protein gene expression in astrocytes differentiated from cortical precursor cells. J Neurochem. 2006;97:1057-70 pubmed
    The elucidation of the transcriptional mechanisms that regulate glial fibrillary acidic protein (GFAP) gene expression is important for the understanding of the molecular mechanisms that control astrocyte differentiation during brain ..
  14. Bernal G, Peterson D. Phenotypic and gene expression modification with normal brain aging in GFAP-positive astrocytes and neural stem cells. Aging Cell. 2011;10:466-82 pubmed publisher
    ..Identified by glial fibrillary acidic protein (GFAP) expression, astrocytes exhibit heterogeneity in morphology and in the expression of phenotypic ..
  15. Shimozaki K, Clemenson G, Gage F. Paired related homeobox protein 1 is a regulator of stemness in adult neural stem/progenitor cells. J Neurosci. 2013;33:4066-75 pubmed publisher
    ..In addition, we find that Prx1 protein is expressed in Sox2(+)/GFAP(+)/Nestin(+) astrocytes in the germinal regions of the adult mouse forebrain...
  16. Lee I, Lee H, Kim J, Chae E, Kim S, Chang N. Short-term hyperhomocysteinemia-induced oxidative stress activates retinal glial cells and increases vascular endothelial growth factor expression in rat retina. Biosci Biotechnol Biochem. 2007;71:1203-10 pubmed
    ..The rats fed the homocystine-diet showed an increase in vimentin, glial fibrillary acidic protein (GFAP), and VEGF immunoreactivity in the retina as compared to the controls...
  17. Hou D, Wan S, Zhou J, Chen K, Tian Y. [Effect of butylphthalide on the expression of S100 and glial fibrillary acidic protein in a rat model of Alzheimer disease]. Nan Fang Yi Ke Da Xue Xue Bao. 2009;29:1147-9 pubmed
    To determine the expression of S100-beta protein and glial fibrillary acidic protein (GFAP) in hippocampal astrocytes of rats with Alzheimer disease (AD) model rats, and observe the effect of butylphthalide on their expression...
  18. Sun L, Min L, Zhou H, Li M, Shao F, Wang W. Adolescent social isolation affects schizophrenia-like behavior and astrocyte biomarkers in the PFC of adult rats. Behav Brain Res. 2017;333:258-266 pubmed publisher
    ..differentially expressed between the SR group and the IR group, the most remarkable of which were glial fibrillary acidic protein (GFAP), Annexin A2 (ANXA2) and vimentin (VIM), three astrocyte biomarkers...
  19. Miyako H, Suzuki A, Nozawa Inoue K, Magara J, Kawano Y, Ono K, et al. Phenotypes of articular disc cells in the rat temporomandibular joint as demonstrated by immunohistochemistry for nestin and GFAP. J Anat. 2011;219:472-80 pubmed publisher
    ..In this immunocytochemical study we examined the localization and distribution patterns of nestin and glial fibrillary acidic protein (GFAP) in the articular disc of the rat temporomandibular joint at postnatal day 1, and weeks 1, 2, 4 ..
  20. Hajos F. Changes in glial fibrillary acidic protein (GFAP) immonureactivity reflect neuronal states. Neurochem Res. 2008;33:1643-50 pubmed publisher
    The astroglial marker, glial fibrillary acidic protein (GFAP) was investigated by immunohistochemistry in various brain areas in order to see its fluctuations in various functional states...
  21. Molthagen M, Schachner M, Bartsch U. Apoptotic cell death of photoreceptor cells in mice deficient for the adhesion molecule on glia (AMOG, the beta 2- subunit of the Na, K-ATPase). J Neurocytol. 1996;25:243-55 pubmed
    ..of photoreceptor cells in the mutant at postnatal day 16 correlated with elevated levels of glial fibrillary acidic protein in retinal astrocytes and with expression of this protein by Muller cells...
  22. Chen J, Zhang J, Zhao Y, Yuan L, Nie X, Li J, et al. Hyperalgesia in response to traumatic occlusion and GFAP expression in rat parabrachial [correction of parabranchial] nucleus: modulation with fluorocitrate. Cell Tissue Res. 2007;329:231-7 pubmed
    ..The expression of glial fibrillary acidic protein (GFAP) in PBN of ipsilateral and contralateral sides was up-regulated 4 h after occlusal changes in ..
  23. Zhang C, Li Y. [The expression of GFAP after brain concussion in rats]. Fa Yi Xue Za Zhi. 2006;22:88-9, 92 pubmed
    To study the expression of GFAP and pathologic changes after rats brain concussion, so that to provide evidence on brain concussion for forensic identification...
  24. Gimenez y Ribotta M, Langa F, Menet V, Privat A. Comparative anatomy of the cerebellar cortex in mice lacking vimentin, GFAP, and both vimentin and GFAP. Glia. 2000;31:69-83 pubmed
    In the cerebellum of adult mammals, glial fibrillary acidic protein (GFAP) and vimentin (VIM) are coexpressed in Golgi epithelial cells (GEC), also known as Bergmann glia...
  25. Sun Y, Luo J, Rao Z, Lan L, Duan L. GFAP and Fos immunoreactivity in lumbo-sacral spinal cord and medulla oblongata after chronic colonic inflammation in rats. World J Gastroenterol. 2005;11:4827-32 pubmed
    ..the lumbo-sacral spinal cord and medulla oblongata were removed and processed for anti-glial fibrillary acidic protein (GFAP), Fos and GFAP/Fos immunohistochemistry...
  26. Lim M, Maubach G, Zhuo L. Glial fibrillary acidic protein splice variants in hepatic stellate cells--expression and regulation. Mol Cells. 2008;25:376-84 pubmed
    The glial fibrillary acidic protein (GFAP) is traditionally used as a marker for astrocytes of the brain, and more recently for the hepatic stellate cells (HSCs) of the liver...
  27. Liu X, Hou D, Wang J, Lv C, Jia S, Zhang Y, et al. Expression of glial fibrillary acidic protein in astrocytes of rat supraoptic nucleus throughout estrous cycle. Neuro Endocrinol Lett. 2016;37:41-5 pubmed
    ..preovulatory luteinizing hormone surge in animals and humans while brain OXT production depends on glial fibrillary acidic protein (GFAP)-associated astrocytic plasticity...
  28. Di Pietro V, Amorini A, Lazzarino G, Yakoub K, D Urso S, Lazzarino G, et al. S100B and Glial Fibrillary Acidic Protein as Indexes to Monitor Damage Severity in an In Vitro Model of Traumatic Brain Injury. Neurochem Res. 2015;40:991-9 pubmed publisher
    ..There is great interest in S100B and Glial Fibrillary Acid Protein (GFAP) as candidate biomarkers of TBI for diagnosis, triage, prognostication and drug development...
  29. Araya Callis C, Hiemke C, Abumaria N, Flugge G. Chronic psychosocial stress and citalopram modulate the expression of the glial proteins GFAP and NDRG2 in the hippocampus. Psychopharmacology (Berl). 2012;224:209-22 pubmed publisher
    ..It has been suggested that there are causal relationships between alterations in brain glia and major depression...
  30. Hughes E, Maguire J, McMinn M, Scholz R, Sutherland M. Loss of glial fibrillary acidic protein results in decreased glutamate transport and inhibition of PKA-induced EAAT2 cell surface trafficking. Brain Res Mol Brain Res. 2004;124:114-23 pubmed
    Loss of the astrocyte-specific intermediate filament protein, glial fibrillary acidic protein (GFAP) results in an increased susceptibility to ischemic insult, enhanced hippocampal LTP, and decreased cerebellar long-term depression (LTD)...
  31. Hu Z, Huang J, Fang M, Wang J, Li Y, Wu L, et al. [Alterations of glial fibrillary acidic protein expression and neural apoptosis in brain of rat offspring born by cesarean section]. Zhonghua Fu Chan Ke Za Zhi. 2010;45:843-7 pubmed
    To study changes of glial fibrillary acidic protein (GFAP) expression and neural apoptosis in rat hippocampus and cortex of cesarean delivered offspring...
  32. Lastres Becker I, Fernandez Perez A, Cebolla B, Vallejo M. Pituitary adenylate cyclase-activating polypeptide stimulates glial fibrillary acidic protein gene expression in cortical precursor cells by activating Ras and Rap1. Mol Cell Neurosci. 2008;39:291-301 pubmed publisher
    Pituitary adenylate cyclase-activating polypeptide (PACAP) acts on cortical precursor cells to trigger glial fibrillary acidic protein (GFAP) gene expression and astrocyte differentiation by stimulation of intracellular cAMP production...
  33. Ekmark Lewén S, Lewén A, Israelsson C, Li G, Farooque M, Olsson Y, et al. Vimentin and GFAP responses in astrocytes after contusion trauma to the murine brain. Restor Neurol Neurosci. 2010;28:311-21 pubmed publisher
    ..The aims for this study were to compare the temporal and spatial expression pattern of vimentin- and glial fibrillary acidic protein (GFAP) in a weight drop model of mild cerebral contusion injury in the rat...
  34. Reuss B, Dono R, Unsicker K. Functions of fibroblast growth factor (FGF)-2 and FGF-5 in astroglial differentiation and blood-brain barrier permeability: evidence from mouse mutants. J Neurosci. 2003;23:6404-12 pubmed
    ..Using FGF-2 and FGF-5 single- and double mutant mice we show now a region-specific reduction of glial fibrillary acidic protein (GFAP), but not of S100 in gray matter astrocytes...
  35. Baldwin S, Scheff S. Intermediate filament change in astrocytes following mild cortical contusion. Glia. 1996;16:266-75 pubmed
    ..They upregulate astrocytic-specific intermediate filament glial fibrillary acidic protein (GFAP) and show a positive signal for the intermediate filament vimentin, a protein primarily found ..
  36. Taft J, Vertes R, Perry G. Distribution of GFAP+ astrocytes in adult and neonatal rat brain. Int J Neurosci. 2005;115:1333-43 pubmed
    ..However, little is known about the normal distribution of GFAP+ astrocytes especially during development...
  37. Takemura M, Gomi H, Colucci Guyon E, Itohara S. Protective role of phosphorylation in turnover of glial fibrillary acidic protein in mice. J Neurosci. 2002;22:6972-9 pubmed
    b>Glial fibrillary acidic protein (GFAP), the principal intermediate filament (IF) protein of mature astrocytes in the CNS, plays specific roles in astrocyte functions. GFAP has multiple phosphorylation sites at its N-terminal head domain...
  38. Dibas A, Yang M, He S, Bobich J, Yorio T. Changes in ocular aquaporin-4 (AQP4) expression following retinal injury. Mol Vis. 2008;14:1770-83 pubmed
    ..Immunohistochemistry using a combination of glial fibrillary acidic protein (GFAP) and aquaporin-4 antibodies were employed to follow changes in the optic nerve head astrocytes...
  39. Shapiro L, Korn M, Shan Z, Ribak C. GFAP-expressing radial glia-like cell bodies are involved in a one-to-one relationship with doublecortin-immunolabeled newborn neurons in the adult dentate gyrus. Brain Res. 2005;1040:81-91 pubmed
    ..for newly born neurons using doublecortin, as well as double labeling using an additional antibody to glial fibrillary acidic protein (GFAP) to label astrocytes were used at the light microscopic level...
  40. Condorelli D, Nicoletti V, Barresi V, Conticello S, Caruso A, Tendi E, et al. Structural features of the rat GFAP gene and identification of a novel alternative transcript. J Neurosci Res. 1999;56:219-28 pubmed
    The glial fibrillary acidic protein (GFAP) is expressed in a cell-specific manner and represents the major subunit of intermediate filaments of astroglial cells...
  41. Afsari Z, Renno W, Abd El Basset E. Alteration of glial fibrillary acidic proteins immunoreactivity in astrocytes of the spinal cord diabetic rats. Anat Rec (Hoboken). 2008;291:390-9 pubmed publisher
    ..A key indicator of this response is the alteration in the level of intermediate filament glial fibrillary acidic protein (GFAP) and number of GFAP-immunoreactive astrocytes...
  42. Carballo Quintás M, Martínez Silva I, Cadarso Suarez C, Alvarez Figueiras M, Ares Pena F, Lopez Martin E. A study of neurotoxic biomarkers, c-fos and GFAP after acute exposure to GSM radiation at 900 MHz in the picrotoxin model of rat brains. Neurotoxicology. 2011;32:478-94 pubmed publisher
    ..anatomical areas to measure induction of the c-fos neuronal marker after 90min and 24h, and of the glial fibrillary acidic protein (GFAP) 72h after acute exposure to a 900MHz electromagnetic field (EMF)...
  43. Stegeman S, Jolly L, Premarathne S, Gecz J, Richards L, Mackay Sim A, et al. Loss of Usp9x disrupts cortical architecture, hippocampal development and TGF?-mediated axonogenesis. PLoS ONE. 2013;8:e68287 pubmed publisher
    ..This study establishes that Usp9x is critical for several aspects of CNS development, and suggests that its regulation of Tgf-? signaling extends to neurons. ..
  44. Berdugo Vega G, Arias Gil G, Rodriguez Niedenführ M, Davies D, Vázquez T, Pascual Font A. GFAP immunoreactivity within the rat nucleus ambiguus after laryngeal nerve injury. J Anat. 2014;225:492-501 pubmed publisher
    ..After 3, 7, 14, 28 or 56 days of survival, the nucleus ambiguus was investigated by means of glial fibrillary acidic protein (GFAP) immunofluorescence or a combination of GFAP immunofluorescence and the application of ..
  45. Xilouri M, Stefanis L. Chaperone mediated autophagy to the rescue: A new-fangled target for the treatment of neurodegenerative diseases. Mol Cell Neurosci. 2015;66:29-36 pubmed publisher
    ..This article is part of Special Issue entitled "Neuronal Protein". ..
  46. Zhang L, Guo Y, Hu H, Wang J, Liu Z, Gao F. FDG-PET and NeuN-GFAP immunohistochemistry of hippocampus at different phases of the pilocarpine model of temporal lobe epilepsy. Int J Med Sci. 2015;12:288-94 pubmed publisher
    ..imaging data were correlated with the immunoreactivity of neuron-specific nuclear protein (NeuN) and glial fibrillary acidic protein (GFAP) in the hippocampus at each time point...
  47. Cascante A, Klum S, Biswas M, Antolin Fontes B, Barnabe Heider F, Hermanson O. Gene-specific methylation control of H3K9 and H3K36 on neurotrophic BDNF versus astroglial GFAP genes by KDM4A/C regulates neural stem cell differentiation. J Mol Biol. 2014;426:3467-77 pubmed publisher
    ..demethylation and loss of RNA polymerase II recruitment in transcribed regions of the astrocyte-characteristic gene GFAP, thereby in parallel repressing astrocytic differentiation by control of elongation...
  48. Sarkar S, Raymick J, Schmued L. Temporal progression of kainic acid induced changes in vascular laminin expression in rat brain with neuronal and glial correlates. Curr Neurovasc Res. 2012;9:110-9 pubmed
    ..the nature and possible underlying mechanism of action of the changes in laminin expression, both Fluoro-Jade C and GFAP immunohistochemistry were employed respectively at all survival intervals...
  49. Eiraku M, Tohgo A, Ono K, Kaneko M, Fujishima K, Hirano T, et al. DNER acts as a neuron-specific Notch ligand during Bergmann glial development. Nat Neurosci. 2005;8:873-80 pubmed
    ..Thus, DNER mediates neuron-glia interaction and promotes morphological differentiation of Bergmann glia through Deltex-dependent Notch signaling. ..
  50. Pekny M, Johansson C, Eliasson C, Stakeberg J, Wallen A, Perlmann T, et al. Abnormal reaction to central nervous system injury in mice lacking glial fibrillary acidic protein and vimentin. J Cell Biol. 1999;145:503-14 pubmed
    ..system, astrocytes become reactive and express high levels of the intermediate filament (IF) proteins glial fibrillary acidic protein (GFAP), vimentin, and nestin...
  51. Arias C, Zepeda A, Hernández Ortega K, Leal Galicia P, Lojero C, Camacho Arroyo I. Sex and estrous cycle-dependent differences in glial fibrillary acidic protein immunoreactivity in the adult rat hippocampus. Horm Behav. 2009;55:257-63 pubmed publisher
    ..have been reported in several species, but it is unknown whether a sexual dimorphism exists in glial fibrillary acidic protein (GFAP) expression in the rat hippocampus...
  52. Brouns R, De Vil B, Cras P, De Surgeloose D, Mariën P, De Deyn P. Neurobiochemical markers of brain damage in cerebrospinal fluid of acute ischemic stroke patients. Clin Chem. 2010;56:451-8 pubmed publisher
    ..We investigated CSF concentrations of myelin basic protein (MBP), glial fibrillary astrocytic protein (GFAP), the calcium-binding protein S100B, and neuron-specific enolase (NSE) in acute ischemic stroke patients and their ..
  53. Ruzza P, Vitale R, Hussain R, Biondi B, Amodeo P, Sechi G, et al. Interactions of GFAP with ceftriaxone and phenytoin: SRCD and molecular docking and dynamic simulation. Biochim Biophys Acta. 2016;1860:2239-48 pubmed publisher
    GFAP is the major intermediate filament protein in mature astrocytes...