Gene Symbol: Fgf13
Description: fibroblast growth factor 13
Alias: FGF-13, fibroblast growth factor 13
Wittmack E, Rush A, Craner M, Goldfarb M, Waxman S, Dib Hajj S. Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons. J Neurosci. 2004;24:6765-75 pubmed
..The preferential expression of FHF2B in sensory neurons may provide a basis for physiological differences in sodium currents that have been reported at the nodes of Ranvier in sensory versus motor axons. ..
Wang C, Hennessey J, Kirkton R, Wang C, Graham V, Puranam R, et al
. Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts. Circ Res. 2011;109:775-82 pubmed publisher
..We tested whether FHFs regulate Na(+) channels in murine heart. We demonstrated that isoforms of FGF13 are the predominant FHFs in adult mouse ventricular myocytes...
Greene J, Li Y, Yourey P, Gruber J, Carter K, Shell B, et al
. Identification and characterization of a novel member of the fibroblast growth factor family. Eur J Neurosci. 1998;10:1911-25 pubmed
..We have identified a novel member of the FGF family that is expressed in the central nervous system (CNS) and increases the number as well as the level of phenotypic differentiation of cortical neurons in vitro. ..
Wu Q, Yang L, Li S, Wang Q, Yuan X, Gao X, et al
. Fibroblast growth factor 13 is a microtubule-stabilizing protein regulating neuronal polarization and migration. Cell. 2012;149:1549-64 pubmed publisher
..b>FGF13, a nonsecretory protein of the FGF family, is expressed in cerebral cortical neurons during development and is a ..
Schoorlemmer J, Goldfarb M. Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinase. J Biol Chem. 2002;277:49111-9 pubmed
..These results support the existence of a signaling module in which IB2 scaffolds a MLK3/MKK/p38delta kinase cascade. FHFs aid in recruitment of p38 to IB2 and may serve as kinase substrates. ..
Irwin L, Byers D. Novel odors affect gene expression for cytokines and proteinases in the rat amygdala and hippocampus. Brain Res. 2012;1489:1-7 pubmed publisher
..amygdala significant up-regulation of interleukin-1 receptor 1 (IL1r1), interleukin-4 receptor (IL4r), fibroblast growth factor 13 (FGF13), and cathepsin-H (CtsH) was observed in males in response to the odor of cornnuts only...
Hennessey J, Wei E, Pitt G. Fibroblast growth factor homologous factors modulate cardiac calcium channels. Circ Res. 2013;113:381-8 pubmed publisher
..Affinity purification of FGF13 from rodent ventricular lysates followed by mass spectroscopy revealed an interaction with junctophilin-2, a ..
Smallwood P, Munoz Sanjuan I, Tong P, Macke J, Hendry S, Gilbert D, et al
. Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development. Proc Natl Acad Sci U S A. 1996;93:9850-7 pubmed
..Each FHF is expressed in the developing and adult nervous systems, suggesting a role for this branch of the FGF family in nervous system development and function. ..
Munoz Sanjuan I, Smallwood P, Nathans J. Isoform diversity among fibroblast growth factor homologous factors is generated by alternative promoter usage and differential splicing. J Biol Chem. 2000;275:2589-97 pubmed