Genomes and Genes
Gene Symbol: E2f5
Description: E2F transcription factor 5
Alias: E2f-5, transcription factor E2F5
- Hayashi R, Goto Y, Haga A, Kobayashi D, Ikeda R, Yoshida K. Comparative genomics on MCM8 orthologous genes reveals the transcriptional regulation by transcription factor E2F. Gene. 2006;367:126-34 pubmed..We also showed that the transcription of human MCM8 is activated by transcription factors E2F1-4, but not by factors E2F5-8.
- Ebelt H, Liu Z, Muller Werdan U, Werdan K, Braun T. Making omelets without breaking eggs: E2F-mediated induction of cardiomyoycte cell proliferation without stimulation of apoptosis. Cell Cycle. 2006;5:2436-9 pubmed..are classified as "activating" E2Fs since they induce proliferation of quiescent cells whereas E2F4 and E2F5 do not have the power to incite cell cycle progression but are related to differentiation processes and were ..
- Itoh A, Levinson S, Morita T, Kourembanas S, Brody J, Mitsialis S. Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors. Cell Mol Biol Res. 1995;41:147-54 pubmed..The structural divergence between the two branches of the E2F family may thus reflect participation in different regulatory networks. ..
- Nili E, Cojocaru G, Kalma Y, Ginsberg D, Copeland N, Gilbert D, et al. Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less). J Cell Sci. 2001;114:3297-307 pubmed..Co-expression of both LAP2beta and mGCL with the E2F-DP complex resulted in a reduced transcriptional activity equal to that exerted by the pRb protein. ..