Dusp13

Summary

Gene Symbol: Dusp13
Description: dual specificity phosphatase 13
Alias: muscle-restricted dual specificity phosphatase, testis and skeletal muscle-specific dual specificity phosphatase
Species: rat
Products:     Dusp13

Top Publications

  1. Nakamura K, Shima H, Watanabe M, Haneji T, Kikuchi K. Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis. Biochem J. 1999;344 Pt 3:819-25 pubmed
    ..These data demonstrate that TMDP is a novel DSP abundantly expressed in the testis and suggest that TMDP may be involved in the regulation of meiosis and/or differentiation of testicular germ cells during spermatogenesis. ..
  2. Aoki N, Aoyama K, Nagata M, Matsuda T. A growing family of dual specificity phosphatases with low molecular masses. J Biochem. 2001;130:133-40 pubmed
    ..Taken together, it is conceivable that a distinct class of low molecular mass DSPs is present and plays a role in dephosphorylating unknown molecules other than MAP kinases. ..
  3. Chen H, Luche R, Wei B, Tonks N. Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2. J Biol Chem. 2004;279:41404-13 pubmed
    ..The conserved gene structure and the similarity in postnatal expression profile of these two proteins suggest biological significance of the unusual gene arrangement. ..
  4. Jeong D, Wei C, Ku B, Jeon T, Chien P, Kim J, et al. The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr D Biol Crystallogr. 2014;70:421-35 pubmed publisher
    ..The family-wide structures of DUSPs form a basis for the understanding of phosphorylation-mediated signal transduction and the development of therapeutics. ..