Gene Symbol: Dusp12
Description: dual specificity phosphatase 12
Alias: GKAP, dual specificity protein phosphatase 12, glucokinase-associated dual specificity phosphatase
Species: rat
Products:     Dusp12

Top Publications

  1. Muda M, Manning E, Orth K, Dixon J. Identification of the human YVH1 protein-tyrosine phosphatase orthologue reveals a novel zinc binding domain essential for in vivo function. J Biol Chem. 1999;274:23991-5 pubmed
    ..Human YVH1 is the first protein-tyrosine phosphatase that contains and is regulated by a zinc finger domain. ..
  2. Muñoz Alonso M, Guillemain G, Kassis N, Girard J, Burnol A, Leturque A. A novel cytosolic dual specificity phosphatase, interacting with glucokinase, increases glucose phosphorylation rate. J Biol Chem. 2000;275:32406-12 pubmed
    ..We called this protein the glucokinase-associated phosphatase (GKAP)...
  3. Aoki N, Aoyama K, Nagata M, Matsuda T. A growing family of dual specificity phosphatases with low molecular masses. J Biochem. 2001;130:133-40 pubmed
    ..LMW-DSP4 exhibited the highest similarity to human YVH1 and rat GKAP, but its C-terminal region was much shorter than that of the human and rat clones...
  4. Jeong D, Wei C, Ku B, Jeon T, Chien P, Kim J, et al. The family-wide structure and function of human dual-specificity protein phosphatases. Acta Crystallogr D Biol Crystallogr. 2014;70:421-35 pubmed publisher
    ..The family-wide structures of DUSPs form a basis for the understanding of phosphorylation-mediated signal transduction and the development of therapeutics. ..