Dpm2

Summary

Gene Symbol: Dpm2
Description: dolichyl-phosphate mannosyltransferase subunit 2, regulatory
Alias: dolichol phosphate-mannose biosynthesis regulatory protein, DPM synthase subunit 2, dolichol-phosphate (beta-D) mannosyltransferase 2, dolichol-phosphate mannose synthase subunit 2, dolichol-phosphate mannosyltransferase 2, dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
Species: rat
Products:     Dpm2

Top Publications

  1. Maeda Y, Tomita S, Watanabe R, Ohishi K, Kinoshita T. DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate. EMBO J. 1998;17:4920-9 pubmed
    ..Here we report expression cloning of a new gene, DPM2, which is defective in Lec15 cells...
  2. Maeda Y, Tanaka S, Hino J, Kangawa K, Kinoshita T. Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3. EMBO J. 2000;19:2475-82 pubmed
    ..We reported previously that mammalian DPM synthase contains catalytic DPM1 and regulatory DPM2 subunits, and that DPM1 requires DPM2 for its stable expression in the endoplasmic reticulum...
  3. Watanabe R, Murakami Y, Marmor M, Inoue N, Maeda Y, Hino J, et al. Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2. EMBO J. 2000;19:4402-11 pubmed
    ..Here, we report that GPI-GnT requires another component, termed PIG-P, and that DPM2, which regulates dolichol-phosphate-mannose synthase, also regulates GPI-GnT...