Genomes and Genes
Gene Symbol: Dmbt1
Description: deleted in malignant brain tumors 1
Alias: Crpd, deleted in malignant brain tumors 1 protein, crp-ductin, deleted in malignant brain tumors 1 protein-like, ebnerin, hensin, pancrin
- Boulatnikov I, De Lisle R. Binding of the Golgi sorting receptor muclin to pancreatic zymogens through sulfated O-linked oligosaccharides. J Biol Chem. 2004;279:40918-26 pubmed..The behavior of Muclin fulfils the requirement of a Golgi cargo receptor to bind to regulated secretory proteins under the mildly acidic pH conditions that exist in the trans-Golgi network. ..
- Takito J, Al Awqati Q. Conversion of ES cells to columnar epithelia by hensin and to squamous epithelia by laminin. J Cell Biol. 2004;166:1093-102 pubmed..Here, we show that mouse embryonic stem cells seeded on hensin or laminin, but not fibronectin or collagen type IV, formed hemispheric epithelial structures whose outermost ..
- Bisgaard H, Holmskov U, Santoni Rugiu E, Nagy P, Nielsen O, Ott P, et al. Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1. Am J Pathol. 2002;161:1187-98 pubmed..Of these, only two, namely alpha-fetoprotein and a novel transcript with high homology to human DMBT1 (deleted in malignant brain tumor 1), were specifically associated with the emergence of ductular (oval) cell ..
- Tynan S, Pacia E, Haynes Johnson D, Lawrence D, D Andrea M, Guo J, et al. The putative tumor suppressor deleted in malignant brain tumors 1 is an estrogen-regulated gene in rodent and primate endometrial epithelium. Endocrinology. 2005;146:1066-73 pubmedDeleted in malignant brain tumors 1 (DMBT1) is a candidate suppressor of malignancies of the brain, lung, gut, and breast. We have been studying gene expression in the uterus in the presence of estrogens and their antagonists...