Decr2

Summary

Gene Symbol: Decr2
Description: 2,4-dienoyl-CoA reductase 2
Alias: Dcrakl, peroxisomal 2,4-dienoyl-CoA reductase, 2,4-dienoyl CoA reductase 2, peroxisomal, 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal, DCR-AKL, pVI-AKL
Species: rat
Products:     Decr2

Top Publications

  1. Fransen M, Van Veldhoven P, Subramani S. Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA reductase. Biochem J. 1999;340 ( Pt 2):561-8 pubmed
  2. Amery L, Mannaerts G, Subramani S, Van Veldhoven P, Fransen M. Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology. Comb Chem High Throughput Screen. 2001;4:545-52 pubmed
    ..These results further demonstrate the suitability of the gVI-cDNA phage display technology for cDNA expression cloning using an antibody as a probe. ..
  3. Das A, Uhler M, Hajra A. Molecular cloning and expression of mammalian peroxisomal trans-2-enoyl-coenzyme A reductase cDNAs. J Biol Chem. 2000;275:24333-40 pubmed publisher
    ..Northern blot analysis demonstrated that a single transcript of 1.3 kilobases is present in most mouse tissues, with particularly high concentrations in liver and kidney...
  4. De Nys K, Meyhi E, Mannaerts G, Fransen M, Van Veldhoven P. Characterisation of human peroxisomal 2,4-dienoyl-CoA reductase. Biochim Biophys Acta. 2001;1533:66-72 pubmed
    ..Hence, the reductase does not seem to constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. The reduction of docosaheptaenoyl-CoA, however, was severely decreased in the presence of albumin. ..