Gene Symbol: Crp
Description: C-reactive protein
Alias: Aa1249, Ab1-341, Ab2-196, Ac1-114, Ac1262, Ac2-069, Ba2-693, C-reactive protein, C-reactive protein, member of the pentraxin family, C-reactive protein, pentraxin-related, C-reactive protein, petaxin related
Species: rat
Products:     Crp

Top Publications

  1. Du Clos T, Zlock L, Hicks P, Mold C. Decreased autoantibody levels and enhanced survival of (NZB x NZW) F1 mice treated with C-reactive protein. Clin Immunol Immunopathol. 1994;70:22-7 pubmed
    C-Reactive protein (CRP) is the prototypic acute-phase serum protein in man. On the basis of its binding specificities and activities, it has been proposed that CRP facilities the removal of nuclear material released from damaged cells...
  2. Rodriguez W, Mold C, Kataranovski M, Hutt J, Marnell L, Du Clos T. Reversal of ongoing proteinuria in autoimmune mice by treatment with C-reactive protein. Arthritis Rheum. 2005;52:642-50 pubmed
    To examine the ability of injection of C-reactive protein (CRP) to treat systemic lupus erythematosus (SLE) in the (NZB x NZW)F(1) (NZB/NZW) mouse and to use a nephrotoxic nephritis (NTN) model to further examine the mechanism of this ..
  3. Andican G, Konukoglu D, Bozluolcay M, Bayulkem K, Firtiına S, Burcak G. Plasma oxidative and inflammatory markers in patients with idiopathic Parkinson's disease. Acta Neurol Belg. 2012;112:155-9 pubmed publisher
    ..Oxidized-LDL (ox-LDL), high-sensitivity C-reactive protein (hs-CRP) and the soluble intracellular adhesion molecule (ICAM) were chosen as biomarkers for systemic inflammation and ..
  4. Isha -, Jain V, Lal H. C-reactive protein and uric Acid levels in patients with psoriasis. Indian J Clin Biochem. 2011;26:309-11 pubmed publisher
    Serum CRP and uric acid levels were estimated in twenty-five patients with psoriasis (group III) before and after 12 weeks of treatment...
  5. Feng X, Xiao J, Longville B, Tan A, Wu X, Cooper M, et al. Complement factor H Y402H and C-reactive protein polymorphism and photodynamic therapy response in age-related macular degeneration. Ophthalmology. 2009;116:1908-12.e1 pubmed publisher
    To investigate the association between complement factor H (CFH) and C-reactive protein (CRP) genotypes and response to photodynamic therapy (PDT) treatment for neovascular age-related macular degeneration (AMD)...
  6. Laurent M, Panayi G. Acute-phase proteins and serum immunoglobulins in ankylosing spondylitis. Ann Rheum Dis. 1983;42:524-8 pubmed
    The erythrocyte sedimentation rate (ESR) and the serum acute-phase proteins (APP), C-reactive protein (CRP), fibrinogen, 9th component of complement (C9), and alpha, antitrypsin were measured on 231 occasions in 80 patients with ..
  7. Coban E, Nizam I, Topal C, Akar Y. The association of low-grade systemic inflammation with hypertensive retinopathy. Clin Exp Hypertens. 2010;32:528-31 pubmed publisher
    High-sensitivity C-reactive protein (hs-CRP) is a marker of systemic low-grade inflammation. The pathophysiologic mechanism of hypertensive retiopathy (HR) is not fully established...
  8. Tan Y, Yu F, Qu Z, Su T, Xing G, Wu L, et al. Modified C-reactive protein might be a target autoantigen of TINU syndrome. Clin J Am Soc Nephrol. 2011;6:93-100 pubmed publisher
    ..05). The staining of mCRP and human IgG were co-localized in renal and ocular tissues. It is concluded that mCRP might be a target autoantigen in TINU syndrome. ..
  9. Drenth J, van Deuren M, van der Ven Jongekrijg J, Schalkwijk C, van der Meer J. Cytokine activation during attacks of the hyperimmunoglobulinemia D and periodic fever syndrome. Blood. 1995;85:3586-93 pubmed
    ..this response is considered to be mediated by cytokines, we measured the acute-phase proteins C-reactive protein (CRP) and soluble type-II phospholipase A2 (PLA2) together with circulating concentrations and ex vivo production of the ..

More Information


  1. Figueredo M, Rodriguez A, Ruiz Yagüe M, Romero M, Fernandez Cruz A, Gomez de la Concha E, et al. Autoantibodies against C-reactive protein: clinical associations in systemic lupus erythematosus and primary antiphospholipid syndrome. J Rheumatol. 2006;33:1980-6 pubmed
    To investigate the prevalence of anti-C-reactive protein (CRP) autoantibodies in patients with systemic lupus erythematosus (SLE) and non-SLE patients with persistent antiphospholipid antibodies (aPL) and their association with clinical ..
  2. Lacoma A, Prat C, Andreo F, Lores L, Ruiz Manzano J, Ausina V, et al. Value of procalcitonin, C-reactive protein, and neopterin in exacerbations of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2011;6:157-69 pubmed publisher
    ..The objective of this study was to investigate whether levels of procalcitonin (PCT), C-reactive protein (CRP), and neopterin in COPD patients could be useful in identifying the etiological origin of the exacerbation and ..
  3. Shaoul R, Lahad A, Tamir A, Lanir A, Srugo I. C reactive protein (CRP) as a predictor for true bacteremia in children. Med Sci Monit. 2008;14:CR255-261 pubmed
    ..We studied the value of CRP compared to total leukocytes (WBC) and absolute neutrophil count (ANC) in differentiating positive, contaminated ..
  4. de Lemos E, Reis F, Baptista S, Pinto R, Sepodes B, Vala H, et al. Exercise training is associated with improved levels of C-reactive protein and adiponectin in ZDF (type 2) diabetic rats. Med Sci Monit. 2007;13:BR168-74 pubmed
    ..This study intended to assess the levels of two inflammatory mediators, C-reactive protein (CRP) and adiponectin, in Zucker Diabetic Fatty (ZDF, fa/fa) rats, an experimental model of T2D, and to determine ..
  5. Job E, Bottazzi B, Gilbertson B, Edenborough K, Brown L, Mantovani A, et al. Serum amyloid P is a sialylated glycoprotein inhibitor of influenza A viruses. PLoS ONE. 2013;8:e59623 pubmed publisher
    ..Given the widespread expression of ?(2,6)-linked sialic acid in the human respiratory tract, we propose that SAP may act as an effective receptor mimic to limit IAV infection of airway epithelial cells. ..
  6. Yanagawa T, Taniguchi A, Fukushima M, Nakai Y, Nagasaka S, Ohgushi M, et al. Leptin, triglycerides, and interleukin 6 are independently associated with C-reactive protein in Japanese type 2 diabetic patients. Diabetes Res Clin Pract. 2007;75:2-6 pubmed
    ..One hundred and 48 Japanese type 2 diabetic patients were studied. In conjunction with C-reactive protein (CRP), BMI, systolic and diastolic blood pressure, glycosylated hemoglobin (HbA1c), fasting concentrations of plasma ..
  7. Costello F, Zimmerman M, Podhajsky P, Hayreh S. Role of thrombocytosis in diagnosis of giant cell arteritis and differentiation of arteritic from non-arteritic anterior ischemic optic neuropathy. Eur J Ophthalmol. 2004;14:245-57 pubmed
    ..ischemic optic neuropathy; and comparison of the sensitivity and specificity of platelet count to that of erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and some other hematologic variables in the diagnosis of GCA.
  8. Tapısız A, Özdemir H, Çiftçi E, Belet N, Ince E, DoÄŸru Ã. Ampicillin/sulbactam for children hospitalized with community-acquired pneumonia. J Infect Chemother. 2011;17:504-9 pubmed publisher
    ..In multivariate analysis, male gender [OR (95%CI): 3.32 (1.37-8.04), p = 0.008], CRP levels [OR (95%CI) 1.04 (1.01-1.08), p = 0.024], and existence of pleural effusion [OR (95%CI) 5.74 (2.17-15...
  9. Steffens S, Kohler A, Rudolph R, Eggers H, Seidel C, Janssen M, et al. Validation of CRP as prognostic marker for renal cell carcinoma in a large series of patients. BMC Cancer. 2012;12:399 pubmed publisher
    To evaluate the prognostic significance of the pre-operative C-reactive protein (CRP) serum level in patients with renal cell cancer (RCC)...
  10. Emokpae M, Uadia P, Gadzama A. Correlation of oxidative stress and inflammatory markers with the severity of sickle cell nephropathy. Ann Afr Med. 2010;9:141-6 pubmed publisher
    ..These parameters correlated with the severity of renal disease. Oxidative stress and inflammatory parameters correlate with sickle cell disease nephropathy. ..
  11. Kinugasa Taniguchi Y, Tomimatsu T, Mimura K, Kanagawa T, Shimoya K, Murata Y, et al. Human C-reactive protein enhances vulnerability of immature rats to hypoxic-ischemic brain damage: a preliminary study. Reprod Sci. 2010;17:419-25 pubmed publisher
    ..rat model of neonatal hypoxic-ischemic (HI) encephalopathy, we investigated the hypothesis that C-reactive protein (CRP), which is not specific for infection, aggravates vulnerability of the immature brain to HI...
  12. Nosrati A, Ben Tov A, Reif S. Diagnostic markers of serious bacterial infections in febrile infants younger than 90 days old. Pediatr Int. 2014;56:47-52 pubmed publisher
    ..laboratory predictors were absolute neutrophil count (ANC), platelets, blood urea nitrogen and C-reactive protein (CRP) level. On receiver operating characteristic curve analysis, the CRP area under the curve (0...
  13. D Alessandris C, Lauro R, Presta I, Sesti G. C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport. Diabetologia. 2007;50:840-9 pubmed
    C-reactive protein (CRP) is associated with insulin resistance and predicts development of type 2 diabetes. However, it is unknown whether CRP directly affects insulin signalling action...
  14. Sjöwall C, Bengtsson A, Sturfelt G, Skogh T. Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus. Arthritis Res Ther. 2004;6:R87-94 pubmed was performed to investigate the relation between IgG autoantibodies against human C-reactive protein (anti-CRP) and disease activity measures in serial serum samples from 10 patients with systemic lupus erythematosus (SLE), of ..
  15. Diepenhorst G, De Graaf W, Niessen H, van Vliet A, Hack C, van Gulik T. Immunoglobulin M, C-reactive protein and complement activation in rat hepatic ischemia-reperfusion injury. Eur Surg Res. 2014;52:50-62 pubmed publisher
    Ischemia-reperfusion (I/R) models have shown that C-reactive protein (CRP) and immunoglobulin M (IgM) are involved in complement activation...
  16. Nowak Ł, Adamczak M, Wiecek A. Is inflammation a new risk factor of depression in haemodialysis patients?. Int Urol Nephrol. 2013;45:1121-8 pubmed publisher
    ..6 %) in haemodialyzed patients in Upper Silesia part of Poland. (2) Catheter placement and inflammation seem to play an important role in the pathogenesis of depression in haemodialysis patients. ..
  17. Dodson P, Shine B. Retinal vein occlusion: C-reactive protein and arterial hypertension. Acta Ophthalmol (Copenh). 1984;62:123-30 pubmed
    ..Serum C-reactive protein (CRP) levels, erythrocyte sedimentation rate (ESR) and plasma viscosity were measured...
  18. Wick M, Grundtman C, Weiss R, Gruber J, Kastlunger M, Jaschke W, et al. The time-averaged inflammatory disease activity estimates the progression of erosions in MRI of the sacroiliac joints in ankylosing spondylitis. Clin Rheumatol. 2012;31:1117-21 pubmed publisher
    ..In each patient, the annual inflammatory disease activity was estimated by the time-averaged C-reactive protein (CRP; mg/l), calculated as the area under the curve. The mean (SD) CRP decreased from 1.3 (1.8) at baseline to 0.5 (0...
  19. Breda L, Di Marzio D, Giannini C, Gaspari S, Nozzi M, Scarinci A, et al. Relationship between inflammatory markers, oxidant-antioxidant status and intima-media thickness in prepubertal children with juvenile idiopathic arthritis. Clin Res Cardiol. 2013;102:63-71 pubmed publisher
    ..Chronic and systemic inflammation seems to lead to early atherosclerotic abnormalities even in pre-pubertal JIA children. Substantial improvement can be obtained with 1-year of appropriate therapy. ..
  20. Leibovitch I, Kurtz S, Kesler A, Feithliher N, Shemesh G, Sela B. C-reactive protein levels in normal tension glaucoma. J Glaucoma. 2005;14:384-6 pubmed
    To determine C-reactive protein (CRP) levels in patients with normal tension glaucoma (NTG). This study included 20 cases with NTG and 30 controls, with no history of ocular disease...
  21. Šilhavý J, Zídek V, Landa V, Šimáková M, Mlejnek P, Oliyarnyk O, et al. Rosuvastatin ameliorates inflammation, renal fat accumulation, and kidney injury in transgenic spontaneously hypertensive rats expressing human C-reactive protein. Physiol Res. 2015;64:295-301 pubmed
    Recently, we derived "humanized" spontaneously hypertensive rats (SHR-CRP) in which transgenic expression of human CRP induces inflammation, oxidative stress, several features of metabolic syndrome and target organ injury...
  22. Seddon J, Gensler G, Rosner B. C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degeneration. Ophthalmology. 2010;117:1560-6 pubmed publisher
    Genetic variants CFH and ARMS2/HTRA1 gene regions as well as high-sensitivity C-reactive protein (CRP) levels are related to age-related macular degeneration (AMD)...
  23. Chatterjee M, Saluja R, Tewari S, Barthwal M, Goel S, Dikshit M. Augmented nitric oxide generation in neutrophils: oxidative and pro-inflammatory implications in hypertension. Free Radic Res. 2009;43:1195-204 pubmed publisher
    ..Levels of TNF-alpha and IFN-gamma were comparable, but IL-1beta and CRP levels in SHR plasma were (p<0.05) elevated...
  24. Nunomura W. C-reactive protein in rat: in development, pregnancy and effect of sex hormones. Comp Biochem Physiol A Comp Physiol. 1990;96:489-93 pubmed
    1. In Wistar strain rats, the serum concentration of C-reactive protein (CRP) was 3.6 +/- 0.8 micrograms/ml at the birth and no apparent change was observed during 15 days after delivery. 2...
  25. Thiele J, Habersberger J, Braig D, Schmidt Y, Goerendt K, Maurer V, et al. Dissociation of pentameric to monomeric C-reactive protein localizes and aggravates inflammation: in vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy. Circulation. 2014;130:35-50 pubmed publisher
    ..mCRP is proposed as a pathogenic factor in atherosclerosis and myocardial infarction. Most importantly, the inhibition of pCRP dissociation represents a promising, novel anti-inflammatory therapeutic strategy...
  26. Moubarak M, Jabbour H, Smayra V, Chouery E, Saliba Y, Jebara V, et al. Cardiorenal syndrome in hypertensive rats: microalbuminuria, inflammation and ventricular hypertrophy. Physiol Res. 2012;61:13-24 pubmed
    ..necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6), brain natriuretic peptide (BNP) and C-reactive protein (CRP). Moreover MA and creatininaemia underwent a significant increase...
  27. Kohli V, Singhi S, Sharma P, Ganguly N. Value of serum C-reactive protein concentrations in febrile children without apparent focus. Ann Trop Paediatr. 1993;13:373-8 pubmed
    We examined the value of serum C-reactive protein (CRP) in febrile children without an apparent focus of infection, (i) as a tool to differentiate bacteraemia and bacterial infection from a non-bacterial illness (NBI), and (ii) as an ..
  28. Cai Y, Fan Y, Wang R, An M, Liang B. Synergistic effects of aminoglycosides and fosfomycin on Pseudomonas aeruginosa in vitro and biofilm infections in a rat model. J Antimicrob Chemother. 2009;64:563-6 pubmed publisher
    ..This offers an effective treatment strategy against some therapy-resistant infections. ..
  29. Holtman L, van Vliet E, Aronica E, Wouters D, Wadman W, Gorter J. Blood plasma inflammation markers during epileptogenesis in post-status epilepticus rat model for temporal lobe epilepsy. Epilepsia. 2013;54:589-95 pubmed publisher
    ..1? (IL-1?), interleukin 6 (IL-6), by enzyme-linked immunosorbent assays (ELISAs) and C-reactive protein (CRP) by immunoturbidimetry, at 1 day after SE (acute period), at 1 week (during the latent period), and at 2 months ..
  30. Al Lawati J, Al Tamtami N, Al Qasmi A, Al Jardani A, Al Abri S, Al Busaidy S. Hospitalised patients with Influenza A (H1N1) in the Royal Hospital, Oman: Experience of a tertiary care hospital, July-December 2009. Sultan Qaboos Univ Med J. 2010;10:326-34 pubmed
    ..Associated medical conditions were common, with pregnancy being interestingly the commonest risk factor. The infection caused severe illness that required ICU admission and led to death in 6.9% of patients. ..
  31. Zhao J, Liu J, Pang X, Zhang X, Wang S, Wu D. Epigallocatechin-3-gallate inhibits angiotensin II-induced C-reactive protein generation through interfering with the AT1-ROS-ERK1/2 signaling pathway in hepatocytes. Naunyn Schmiedebergs Arch Pharmacol. 2016;389:1225-1234 pubmed
    ..As a representative inflammatory molecule, C-reactive protein (CRP) is mainly produced in the liver...
  32. Mookerjea S, Francis J, Hunt D, Yang C, Nagpurkar A. Rat C-reactive protein causes a charge modification of LDL and stimulates its degradation by macrophages. Arterioscler Thromb. 1994;14:282-7 pubmed
    We have previously shown the binding of low-density lipoprotein (LDL) to immobilized rat C-reactive protein (CRP) and the formation of a fluid-phase complex between these two proteins...
  33. Shi M, Cui F, Yang C, Zhang H, Wang Y, Wei L, et al. [Effects of chronic intermittent hypobaric hypoxia on immune function in rat]. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2009;25:433-8 pubmed
    ..CIHH protects the immune function of rat against acute hypoxia, which is related with the regulation of neuroendocrine. ..
  34. Bankier B, Barajas J, Martinez Rumayor A, Januzzi J. Association between C-reactive protein and generalized anxiety disorder in stable coronary heart disease patients. Eur Heart J. 2008;29:2212-7 pubmed publisher
    ..disorder in stable coronary heart disease (CHD) patients, including cardiac biomarkers such as C-reactive protein (CRP), troponin T (TnT), and amino-terminal pro-B-type brain natriuretic peptide (NT-proBNP)...
  35. Rebuzzi A, Quaranta G, Liuzzo G, Caligiuri G, Lanza G, Gallimore J, et al. Incremental prognostic value of serum levels of troponin T and C-reactive protein on admission in patients with unstable angina pectoris. Am J Cardiol. 1998;82:715-9 pubmed
    ..available on admission (pain in the last 24 hours, electrocardiogram [ECG], troponin T, and C-reactive protein [CRP]), and of Holter monitoring available during the subsequent 24 hours was analyzed in 102 patients with Braunwald ..
  36. Wu D, Liu J, Pang X, Wang S, Zhao J, Zhang X, et al. Palmitic acid exerts pro-inflammatory effects on vascular smooth muscle cells by inducing the expression of C-reactive protein, inducible nitric oxide synthase and tumor necrosis factor-α. Int J Mol Med. 2014;34:1706-12 pubmed publisher
    ..purpose of the present study was to observe the effect of palmitic acid on the expression of C-reactive protein (CRP), tumor necrosis factor α (TNF-α) and inducible nitric oxide synthase (iNOS) in VSMCs...
  37. Biljak V, Pancirov D, Cepelak I, Popovic Grle S, Stjepanovic G, Grubisić T. Platelet count, mean platelet volume and smoking status in stable chronic obstructive pulmonary disease. Platelets. 2011;22:466-70 pubmed publisher
    ..count, mean platelet volume (MPV) and classical markers of systemic inflammation - serum C-reactive protein (CRP), white blood cell (WBC) count and the relative proportion of segmented neutrophils in COPD patients, and compared ..
  38. Corsetti J, Gansevoort R, Sparks C, Dullaart R. Inflammation reduces HDL protection against primary cardiac risk. Eur J Clin Invest. 2010;40:483-9 pubmed publisher
    ..risk in a subgroup of postinfarction patients defined by hypercholesterolemia and high C-reactive protein (CRP) levels. We investigated whether a similar high-risk subgroup might exist for incident cardiovascular disease...
  39. Assa A, Hartman C, Weiss B, Broide E, Rosenbach Y, Zevit N, et al. Long-term outcome of tumor necrosis factor alpha antagonist's treatment in pediatric Crohn's disease. J Crohns Colitis. 2013;7:369-76 pubmed publisher
    ..Responders experienced a significant decrease in erythrocyte sedimentation rate (ESR) and C reactive protein (CRP) during treatment (p<0.001)...
  40. Wang C, Liu J, Guo F, Ji Y, Liu N. Endothelin-1 induces the expression of C-reactive protein in rat vascular smooth muscle cells. Biochem Biophys Res Commun. 2009;389:537-42 pubmed publisher
    ..have shown that both vasoconstrictive peptide endothelin-1 (ET-1) and inflammatory marker C-reactive protein (CRP) are implicated in the inflammatory process of atherosclerosis...
  41. Yosef Levi I, Grad E, Danenberg H. [C-reactive protein and atherothrombosis--a prognostic factor or a risk factor?]. Harefuah. 2007;146:970-4, 996 pubmed
    Inflammation plays a role in vascular injury and repair. The inflammatory acute phase protein C-reactive protein (CRP) has emerged as a powerful predictor of cardiovascular events...
  42. Dubsky M, Jirkovska A, Bem R, Fejfarova V, Skibova J, Schaper N, et al. Risk factors for recurrence of diabetic foot ulcers: prospective follow-up analysis in the Eurodiale subgroup. Int Wound J. 2013;10:555-61 pubmed publisher
    ..and alcohol abuse) and DFU-related factors [peripheral arterial disease, ulcer infection, C-reactive protein (CRP) and; foot deformities]. During the 3-year follow-up period, a DFU had recurred in 42 patients (57.5%)...
  43. Sweiss N, Barnathan E, Lo K, Judson M, Baughman R. C-reactive protein predicts response to infliximab in patients with chronic sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2010;27:49-56 pubmed
    ..We evaluated the response to therapy by baseline CRP using a dichotomous cutpoint (0...
  44. Goldenberg Cohen N, Cohen Y, Monselise Y, Eldar I, Axer Siegel R, Weinberger D, et al. C-reactive protein levels do not correlate with retinal artery occlusion but with atherosclerosis. Eye (Lond). 2009;23:785-90 pubmed publisher
    To determine C-reactive protein (CRP) levels in acute retinal artery occlusion (RAO) and their association with atherosclerotic risk factors...
  45. Ahlsson A, Bodin L, Lundblad O, Englund A. Postoperative atrial fibrillation is not correlated to C-reactive protein. Ann Thorac Surg. 2007;83:1332-7 pubmed
    ..differences between patients with and without postoperative AF with special regard to C-reactive protein (CRP) serum levels...
  46. Szalai A, McCrory M, Cooper G, Wu J, Kimberly R. Association between baseline levels of C-reactive protein (CRP) and a dinucleotide repeat polymorphism in the intron of the CRP gene. Genes Immun. 2002;3:14-9 pubmed
    Elevation of baseline C-reactive protein (CRP) is associated with increased risk of cardiac disease. This increase might reflect low-grade inflammation, but differences in CRP serum levels might also have a genetic component...
  47. Unek I, Bayraktar F, Solmaz D, Ellidokuz H, Sisman A, Yuksel F, et al. The levels of soluble CD40 ligand and C-reactive protein in normal weight, overweight and obese people. Clin Med Res. 2010;8:89-95 pubmed publisher
    ..Obese patients showed a significant increase of hsCRP and sCD40L levels compared with normal weight subjects, which might contribute to the known proinflammatory milieu found in these patients. ..
  48. Li Y, Robins J, Ye J, Huang Z, Wen Q, Zhang G. Adaptive diversity of innate immune receptor family short pentraxins in Murinae. FEBS Lett. 2012;586:798-803 pubmed publisher
    The short pentraxins C-reactive protein (CRP) and serum amyloid P component (SAP) constitute a group of innate immune receptors that trigger immune activation by detecting molecules of the microbial cell wall...
  49. Vine A, Stader J, Branham K, Musch D, Swaroop A. Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration. Ophthalmology. 2005;112:2076-80 pubmed
    To measure and contrast 2 biomarkers of cardiovascular disease, C-reactive protein (CRP) and plasma homocysteine, in individuals with age-related macular degeneration (AMD) and control individuals without AMD. Case-control study...
  50. Chung M, Martin D, Sprecher D, Wazni O, Kanderian A, Carnes C, et al. C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation. Circulation. 2001;104:2886-91 pubmed
    ..C-reactive protein (CRP), a marker of systemic inflammation, predicts cardiovascular events and stroke, a common sequela of AF...
  51. Clayton K, Podlesniy P, Figueiro Silva J, López Doménech G, Benitez L, Enguita M, et al. NP1 regulates neuronal activity-dependent accumulation of BAX in mitochondria and mitochondrial dynamics. J Neurosci. 2012;32:1453-66 pubmed publisher
    ..These results show that NP1 is targeted to mitochondria acting upstream of BAX and uncover a novel function for NP1 in the regulation of mitochondrial dynamics and trafficking during apoptotic neurodegeneration. ..
  52. Zhong L, Peng L, Huang H, Liang M, Zhou Q, Zhang B, et al. [Value of fluorescence quantitative PCR assay of bronchoalveolar lavage fluid samples in the diagnosis of Mycoplasma pneumoniae pneumonia in children]. Zhongguo Dang Dai Er Ke Za Zhi. 2011;13:191-4 pubmed
    ..05). The copies of MP-DNA were positively correlated with CRP values (r=0.845, P<0.01). FQ-PCR assay of BALF for detecting MP-DNA in BALF is superior to the serological test...
  53. Sadik N. Chemopreventive efficacy of green tea drinking against 1,2-dimethyl hydrazine-induced rat colon carcinogenesis. Cell Biochem Funct. 2013;31:196-207 pubmed publisher
    ..It can be concluded that green tea exerts a potent chemopreventive effect on colon carcinogenesis possibly due to the inhibition of NF-?B. ..