Gene Symbol: Cops4
Description: COP9 signalosome subunit 4
Alias: COP9 signalosome complex subunit 4, COP9 (constitutive photomorphogenic) homolog, subunit 4, JAB1-containing signalosome subunit 4, SGN4, signalosome subunit 4
Species: rat
Products:     Cops4

Top Publications

  1. Sharon M, Mao H, Boeri Erba E, Stephens E, Zheng N, Robinson C. Symmetrical modularity of the COP9 signalosome complex suggests its multifunctionality. Structure. 2009;17:31-40 pubmed publisher
    ..This suggests that the propensity of the CSN complex to change and adapt its subunit composition might underlie its ability to perform multiple functions in vivo. ..
  2. Granata A, Koo S, Haucke V, Schiavo G, Warner T. CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process. EMBO J. 2011;30:181-93 pubmed publisher
    ..Retrieval of surface-stranded synaptotagmin 1 is restored by overexpression of stonin 2 in ?E-TA-expressing cells, suggesting that the DYT1 mutation compromises the role of TA in protein stabilisation and synaptic vesicle recycling. ..