Genomes and Genes
class I alcohol dehydrogenase
Gene Symbol: class I alcohol dehydrogenase
Description: alcohol dehydrogenase 3
Alias: Adh1c, alcohol dehydrogenase 1C, class I alcohol dehydrogenase
- Glutathione-dependent formaldehyde dehydrogenase (ADH3) and low km mitochondrial aldehyde dehydrogenase (ALDH2). New evidence for differential expression in the rat retina in response to oxidative stressC Galbis-Estrada
Ophthalmic Research Unit Santiago Grisolía, University Hospital Dr Peset, Valencia, Spain
Free Radic Res 46:77-84. 2012..In addition to other pathogenic mechanisms not fully understood, the possibility remains that peroxidic aldehydes, acting as cytotoxic chemicals, mediate in the progression of chronic ocular disorders...
- Structure and expression of the rat class I alcohol dehydrogenase geneD W Crabb
Department of Medicine, Indiana University School of Medicine, Indianapolis 46223
Genomics 5:906-14. 1989Clones containing the rat class I alcohol dehydrogenase (ADH) gene were isolated from a Charon 4A genomic library. The gene spans approximately 13 kb and comprises nine exons and eight introns...
- Role of extrahepatic alcohol dehydrogenase in rat ethanol metabolismM D Boleda
Department de Bioquimica i Biologia Molecular, Facultat de Ciencies, Universitat Autonoma de Barcelona, Bellaterra, Spain
Arch Biochem Biophys 274:74-81. 1989..4 microM) and indicate that at the usual concentration of inhibitor only ADH-3 activity will be effectively suppressed. ADH-1 will be, therefore, responsible in part for the residual ethanol oxidation activity in pyrazole-treated rats...
- Prospective evaluation of the alcohol dehydrogenase gamma1/gamma2 gene polymorphism and risk of strokeRobert Y L Zee
Center for Cardiovascular Disease Prevention and the Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Stroke 35:e39-42. 2004Genetic polymorphism of the alcohol dehydrogenase type 3 gene (ADH1C) has recently been associated with reduced risk of myocardial infarction. However, data on risk of stroke are not available.
- High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract: implications for Parkinson's diseaseMarie Westerlund
Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
FEBS J 274:1212-23. 2007..for the possible involvement of alcohol and aldehyde dehydrogenases (ADH; ALDH) by identifying genetic variants in ADH1C and ADH4 that associate with PD...