Chmp7

Summary

Gene Symbol: Chmp7
Description: charged multivesicular body protein 7
Alias: RGD1308779, charged multivesicular body protein 7, CHMP family, member 7
Species: rat
Products:     Chmp7

Top Publications

  1. Horii M, Shibata H, Kobayashi R, Katoh K, Yorikawa C, Yasuda J, et al. CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway. Biochem J. 2006;400:23-32 pubmed
    ..We have characterized a novel human ESCRT-III-related protein, designated CHMP7, which consists of 453 amino acid residues...
  2. Vietri M, Schink K, Campsteijn C, Wegner C, Schultz S, Christ L, et al. Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing. Nature. 2015;522:231-5 pubmed publisher
    ..associated with diverse cellular activities) ATPase VPS4 are specifically recruited by the ESCRT-III-like protein CHMP7 to sites where the reforming nuclear envelope engulfs spindle microtubules...
  3. Gu M, LaJoie D, Chen O, von Appen A, Ladinsky M, Redd M, et al. LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells. Proc Natl Acad Sci U S A. 2017;114:E2166-E2175 pubmed publisher
    ..LEM (Lap2-Emerin-Man1) family of inner nuclear membrane proteins, and the ESCRT-II/ESCRT-III hybrid protein Cmp7p (CHMP7), work together to recruit additional ESCRT-III proteins to holes in the nuclear membrane...