Gene Symbol: Chmp1a
Description: charged multivesicular body protein 1A
Alias: Pcoln3, charged multivesicular body protein 1a, chromatin modifying protein 1A, procollagen (type III) N-endopeptidase
Stuchell Brereton M, Skalicky J, Kieffer C, Karren M, Ghaffarian S, Sundquist W. ESCRT-III recognition by VPS4 ATPases. Nature. 2007;449:740-4 pubmed
..Structures of VPS4A MIT-CHMP1A and VPS4B MIT-CHMP2B complexes reveal that the C-terminal CHMP motif forms an amphipathic helix that binds in a ..
Ohno T, French L, Hirano S, Ossoff R, Rousseau B. Effect of hepatocyte growth factor on gene expression of extracellular matrix during wound healing of the injured rat vocal fold. Ann Otol Rhinol Laryngol. 2008;117:696-702 pubmed
..Results provide evidence of HGF treatment effects on procollagen type III and HAS-2 gene expression pathways. ..
Bajorek M, Morita E, Skalicky J, Morham S, Babst M, Sundquist W. Biochemical analyses of human IST1 and its function in cytokinesis. Mol Biol Cell. 2009;20:1360-73 pubmed publisher
..In contrast, IST1 depletion did not inhibit human immunodeficiency virus-1 budding. Thus, IST1 and CHMP1 act together to recruit and modulate specific VPS4 activities required during the final stages of cell division. ..
Yoshida H, Haze K, Yanagi H, Yura T, Mori K. Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors. J Biol Chem. 1998;273:33741-9 pubmed
..These results suggest that, as in yeast, bZIP proteins are involved in mammalian UPR, acting through newly defined ERSE. ..
Stauffer D, Howard T, Nyun T, Hollenberg S. CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression. J Cell Sci. 2001;114:2383-93 pubmed
..In combination, these observations suggest that CHMP1 plays a role in stable gene silencing within the nucleus. ..
Howard T, Stauffer D, Degnin C, Hollenberg S. CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins. J Cell Sci. 2001;114:2395-404 pubmed
..These observations identify the conserved CHMP/Chmp family as a set of proteins fundamental to understanding multivesicular body sorting in eukaryotic organisms. ..