Gene Symbol: Cdan1
Description: codanin 1
Alias: codanin-1, LOW QUALITY PROTEIN: codanin-1, congenital dyserythropoietic anemia, type I
Species: rat

Top Publications

  1. Dgany O, Avidan N, Delaunay J, Krasnov T, Shalmon L, Shalev H, et al. Congenital dyserythropoietic anemia type I is caused by mutations in codanin-1. Am J Hum Genet. 2002;71:1467-74 pubmed
    ..CDA type I (CDAI [MIM 224120], gene symbol CDAN1) is characterized by erythroid pathological features such as internuclear chromatin bridges, spongy ..
  2. Tamary H, Dgany O, Proust A, Krasnov T, Avidan N, Eidelitz Markus T, et al. Clinical and molecular variability in congenital dyserythropoietic anaemia type I. Br J Haematol. 2005;130:628-34 pubmed
    ..Complex bone disease has only occasionally been associated with this disease. CDA I is caused by mutations in the CDAN1 gene encoding for codanin-1...
  3. Ask K, Jasencakova Z, Menard P, Feng Y, Almouzni G, Groth A. Codanin-1, mutated in the anaemic disease CDAI, regulates Asf1 function in S-phase histone supply. EMBO J. 2012;31:2013-23 pubmed publisher
    ..This function is compromised by two CDAI mutations that impair complex formation with Asf1, providing insight into the molecular basis for CDAI disease. ..
  4. Renella R, Roberts N, Brown J, De Gobbi M, Bird L, Hassanali T, et al. Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1{alpha} localization in erythroblasts. Blood. 2011;117:6928-38 pubmed publisher
    ..Mice containing a gene-trapped Cdan1 locus demonstrate its widespread expression during development...