C1rl

Summary

Gene Symbol: C1rl
Description: complement C1r subcomponent like
Alias: complement C1r subcomponent-like protein, C1r-LP, C1r-like protein, complement component 1, r subcomponent-like
Species: rat

Top Publications

  1. Circolo A, Garnier G, Volanakis J. A novel murine complement-related gene encoding a C1r-like serum protein. Mol Immunol. 2003;39:899-906 pubmed
  2. Wicher K, Fries E. Prohaptoglobin is proteolytically cleaved in the endoplasmic reticulum by the complement C1r-like protein. Proc Natl Acad Sci U S A. 2004;101:14390-5 pubmed
    ..C1r-LP accounts for at least part of the endogenous proHp-cleavage activity because suppression of the C1r-LP expression by RNA interference reduced the cleavage of proHp by up to 45% in the cells of a human hepatoma cell line (HepG2). ..