Genomes and Genes
beta carotene 15 15 monooxygenase
Gene Symbol: beta carotene 15 15 monooxygenase
Description: beta-carotene oxygenase 1
Alias: Bcdo, Bcmo1, beta,beta-carotene 15,15'-dioxygenase, beta,beta-carotene 15,15'-monooxygenase, beta-carotene 15, 15'-dioxygenase, beta-carotene 15, 15-dioxygenase, beta-carotene 15,15'-monooxygenase 1, beta-carotene dioxygenase 1
- Bachmann H, Desbarats A, Pattison P, Sedgewick M, Riss G, Wyss A, et al. Feedback regulation of beta,beta-carotene 15,15'-monooxygenase by retinoic acid in rats and chickens. J Nutr. 2002;132:3616-22 pubmed..Our data suggest that retinoids and carotenoids might regulate betaCMOOX expression by a transcriptional feedback mechanism via interaction with members of the RAR family. ..
- Takitani K, Miyazaki H, Fukunishi S, Takaya R, Yoden A, Higuchi K, et al. Altered expression of both ?-carotene 15,15' monooxygenase and lecithin:retinol acyltransferase in obese Zucker rats. J Nutr Sci Vitaminol (Tokyo). 2011;57:108-13 pubmed..There was no difference in hepatic CRBP-I and CYP26A1 gene expression between fa/fa rats and lean rats. Altered expression of BCM and LRAT genes may affect plasma retinol status in obesity and dyslipidemia. ..
- Lobo G, Amengual J, Palczewski G, Babino D, von Lintig J. Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasis. Biochim Biophys Acta. 2012;1821:78-87 pubmed publisher..This article is part of a Special Issue entitled Retinoid and Lipid Metabolism. ..
- Mochizuki H, Mochizuki K, Suruga K, Igarashi M, Takase S, Goda T. Induction of the BCMO1 gene during the suckling-weaning transition in rats is associated with histone H3 K4 methylation and subsequent coactivator binding and histone H3 acetylation to the gene. J Nutr Sci Vitaminol (Tokyo). 2012;58:319-26 pubmed..However, the molecular mechanisms involved in the regulation of ?-carotene 15,15'-monooxygenase 1 (BCMO1) gene expression in the small intestine remain unknown...