Gene Symbol: Bet1
Description: Bet1 golgi vesicular membrane trafficking protein
Alias: BET1 homolog, Golgi vesicular membrane-trafficking protein p18, golgi vesicular membrane trafficking protein p18, rBET1
Hay J, Hirling H, Scheller R. Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus. J Biol Chem. 1996;271:5671-9 pubmed
..In this report, we describe rat sec22 (rsec22) and rat bet1 (rbet1), mammalian sequence homologs of yeast proteins identified as mediators of endoplasmic reticulum-to-Golgi protein ..
Xu Y, Wong S, Zhang T, Subramaniam V, Hong W. GS15, a 15-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) homologous to rbet1. J Biol Chem. 1997;272:20162-6 pubmed
..A mammalian protein related to Bet1p has been reported previously and was referred to as rbet1. We have now identified a new mammalian protein that is homologous to rbet1 (28% amino acid identity)...
Zhang T, Wong S, Tang B, Xu Y, Peter F, Subramaniam V, et al
. The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus. J Cell Biol. 1997;139:1157-68 pubmed
..A mammalian protein (rbet1) homologous to Bet1p was recently identified, and it was concluded that rbet1 is associated with the Golgi ..
Steegmaier M, Oorschot V, Klumperman J, Scheller R. Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics. Mol Biol Cell. 2000;11:2719-31 pubmed
..with a syntaxin regulatory protein, rsly1, and/or two intermediate compartment SNARE proteins, rsec22b and rbet1. Furthermore, we found that syntaxin 17 is anchored to the smooth endoplasmic reticulum through an unusual ..
Hay J, Chao D, Kuo C, Scheller R. Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. Cell. 1997;89:149-58 pubmed
..cis-Golgi vesicle receptor syntaxin 5 was found in a complex with Golgi-associated SNARE of 28 kDa (GOS-28), rbet1, rsly1, and two novel proteins characterized herein: rat sec22b and membrin, both cytoplasmically oriented ..
Joglekar A, Xu D, Rigotti D, Fairman R, Hay J. The SNARE motif contributes to rbet1 intracellular targeting and dynamics independently of SNARE interactions. J Biol Chem. 2003;278:14121-33 pubmed
The endoplasmic reticulum/Golgi SNARE rbet1 cycles between the endoplasmic reticulum and Golgi and is essential for cargo transport in the secretory pathway...
Loh E, Peter F, Subramaniam V, Hong W. Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. J Cell Sci. 2005;118:1209-22 pubmed
..Gel filtration analysis demonstrates that Bet3 exists in two distinct pools in the cytosol, the high-molecular-weight pool may represent the TRAPP complex, whereas the other probably represents the monomeric Bet3. ..
Siddiqi S, Siddiqi S, Mahan J, Peggs K, Gorelick F, Mansbach C. The identification of a novel endoplasmic reticulum to Golgi SNARE complex used by the prechylomicron transport vesicle. J Biol Chem. 2006;281:20974-82 pubmed
..docked with cis-Golgi, were solubilized in 2% Triton X-100, and proteins were immunoprecipitated using VAMP7 or rBet1 antibodies. In both cases, a 112-kDa complex was identified in nonboiled samples that dissociated upon boiling...