Banf1

Summary

Gene Symbol: Banf1
Description: barrier to autointegration factor 1
Alias: Baf, Bcrp1, L2bp1, L2bp1/Baf, barrier-to-autointegration factor, Breakpoint cluster region protein, uterine leiomyoma, 1, Breakpoint cluster region protein, uterine leiomyoma, 1; barrier to autointegration factor, LAP2-binding protein 1, Lap2 binding protein 1, breakpoint cluster region protein 1
Species: rat
Products:     Banf1

Top Publications

  1. Dechat T, Gajewski A, Korbei B, Gerlich D, Daigle N, Haraguchi T, et al. LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly. J Cell Sci. 2004;117:6117-28 pubmed
    ..Furthermore, the DNA-crosslinking protein barrier-to-autointegration factor (BAF) bound to LAP2alpha in vitro and in mitotic extracts, and subfractions of BAF relocalized to core structures with ..
  2. Lee M, Craigie R. A previously unidentified host protein protects retroviral DNA from autointegration. Proc Natl Acad Sci U S A. 1998;95:1528-33 pubmed
    ..The identity of the protein was confirmed by expressing it in Escherichia coli and demonstrating the activity of the heterologously expressed protein in the reconstitution assay. ..
  3. Furukawa K. LAP2 binding protein 1 (L2BP1/BAF) is a candidate mediator of LAP2-chromatin interaction. J Cell Sci. 1999;112 ( Pt 15):2485-92 pubmed
    ..Here I identified a LAP2 interacting protein, termed L2BP1 (LAP2 binding protein 1)...
  4. Bradley C, Ronning D, Ghirlando R, Craigie R, Dyda F. Structural basis for DNA bridging by barrier-to-autointegration factor. Nat Struct Mol Biol. 2005;12:935-6 pubmed
    The ability of barrier-to-autointegration factor (BAF) to bind and bridge DNA in a sequence-independent manner is crucial for its role in retroviral integration and a variety of cellular processes...
  5. Wiebe M, Traktman P. Poxviral B1 kinase overcomes barrier to autointegration factor, a host defense against virus replication. Cell Host Microbe. 2007;1:187-97 pubmed publisher
    b>Barrier to autointegration factor (BAF) is a DNA-binding protein found in the nucleus and cytoplasm of eukaryotic cells that functions to establish nuclear architecture during mitosis...
  6. Kim W, Chakraborty G, Kim S, Shin J, Park C, Jeong M, et al. Macro histone H2A1.2 (macroH2A1) protein suppresses mitotic kinase VRK1 during interphase. J Biol Chem. 2012;287:5278-89 pubmed publisher
    ..2 by NMR spectroscopy. Hence, our findings might provide valuable insight into the underlying molecular mechanism regarding an epigenetic regulation of histone H3 during the cell cycle. ..
  7. Brachner A, Braun J, Ghodgaonkar M, Castor D, Zlopasa L, Ehrlich V, et al. The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo. J Cell Sci. 2012;125:1048-57 pubmed publisher
    ..interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF)...