B4gat1

Summary

Gene Symbol: B4gat1
Description: beta-1,4-glucuronyltransferase 1
Alias: B3gnt1, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
Species: rat

Top Publications

  1. Praissman J, Live D, Wang S, Ramiah A, Chinoy Z, Boons G, et al. B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan. elife. 2014;3: pubmed publisher
    ..with catalytic activity towards β-galactose but rather a β-1,4-glucuronyltransferase, designated B4GAT1, towards both α- and β-anomers of xylose...
  2. Willer T, Inamori K, Venzke D, Harvey C, Morgensen G, Hara Y, et al. The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation. elife. 2014;3: pubmed publisher
    ..Here we show that FKRP, FKTN, TMEM5 and B4GAT1 (formerly known as B3GNT1) localize to the Golgi and contribute to the O-mannosyl post-phosphorylation modification of α-DG...
  3. Wright K, Lyon K, Leung H, Leahy D, Ma L, Ginty D. Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron. 2012;76:931-44 pubmed publisher
    ..Using a murine forward genetic screen for novel determinants of axon guidance, we identified B3gnt1 and ISPD as required for the glycosylation of dystroglycan in vivo...