B3galnt2

Summary

Gene Symbol: B3galnt2
Description: beta-1,3-N-acetylgalactosaminyltransferase 2
Alias: RGD1306946, UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2, UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2
Species: rat
Products:     B3galnt2

Top Publications

  1. Stevens E, Carss K, Cirak S, Foley A, Torelli S, Willer T, et al. Mutations in B3GALNT2 cause congenital muscular dystrophy and hypoglycosylation of ?-dystroglycan. Am J Hum Genet. 2013;92:354-65 pubmed publisher
    ..two individuals affected by a dystroglycanopathy with mutations in ?-1,3-N-acetylgalactosaminyltransferase 2 (B3GALNT2). B3GALNT2 transfers N-acetyl galactosamine (GalNAc) in a ?-1,3 linkage to N-acetyl glucosamine (GlcNAc)...
  2. Yoshida Moriguchi T, Willer T, Anderson M, Venzke D, Whyte T, Muntoni F, et al. SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function. Science. 2013;341:896-9 pubmed publisher
    ..1,4-N-acetylglucosaminyltransferase whose product could be extended by ? 1,3-N-acetylgalactosaminyltransferase2 (B3GALNT2) to form the O-mannosyl trisaccharide...