Gene Symbol: Ap1s1
Description: adaptor-related protein complex 1, sigma 1 subunit
Alias: Ube2w, ubiquitin-conjugating enzyme E2 W, E2 ubiquitin-conjugating enzyme W, N-terminal E2 ubiquitin-conjugating enzyme, N-terminus-conjugating E2, adaptor protein complex AP-1, sigma 1, ubiquitin carrier protein W, ubiquitin-protein ligase W
Species: rat
Products:     Ap1s1

Top Publications

  1. Baltes J, Larsen J, Radhakrishnan K, Geumann C, Kratzke M, Petersen C, et al. ?1B adaptin regulates adipogenesis by mediating the sorting of sortilin in adipose tissue. J Cell Sci. 2014;127:3477-87 pubmed publisher
    ..Vertebrates express three AP1 ?1 subunit isoforms - ?1A, ?1B and ?1C (also known as AP1S1, AP1S2 and AP1S3, respectively)...
  2. Jain S, Farías G, Bonifacino J. Polarized sorting of the copper transporter ATP7B in neurons mediated by recognition of a dileucine signal by AP-1. Mol Biol Cell. 2015;26:218-28 pubmed publisher
  3. Page L, Sowerby P, Lui W, Robinson M. Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin. J Cell Biol. 1999;146:993-1004 pubmed
    ..The presence of an EH domain suggests that gamma-synergin links the AP-1 complex to another protein or proteins. ..
  4. Glyvuk N, Tsytsyura Y, Geumann C, D Hooge R, Hüve J, Kratzke M, et al. AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory. EMBO J. 2010;29:1318-30 pubmed publisher
    ..The sigma1B-deficient mice have reduced motor coordination and severely impaired long-term spatial memory. These data reveal a molecular mechanism for a severe human X-chromosome-linked mental retardation. ..