Genomes and Genes
Gene Symbol: Agl
Description: amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Alias: glycogen debranching enzyme, amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III), amylo-1,6-glucosidase, 4-alpha-glucanotransferase
- Cheng A, Zhang M, Gentry M, Worby C, Dixon J, Saltiel A. A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev. 2007;21:2399-409 pubmedCori's disease is a glycogen storage disorder characterized by a deficiency in the glycogen debranching enzyme, amylo-1,6-glucosidase,4-alpha-glucanotransferase (AGL)...
- Satoh K, Sato K. Glycogen-binding protein components of rat tissues. Biochem Biophys Res Commun. 1980;96:28-33 pubmed
- Shen J, Bao Y, Liu H, Lee P, Leonard J, Chen Y. Mutations in exon 3 of the glycogen debranching enzyme gene are associated with glycogen storage disease type III that is differentially expressed in liver and muscle. J Clin Invest. 1996;98:352-7 pubmedGlycogen storage disease type HI (GSD-III), an autosomal recessive disease, is caused by deficient glycogen debranching enzyme (GDE) activity...