Acad9

Summary

Gene Symbol: Acad9
Description: acyl-CoA dehydrogenase family, member 9
Alias: Nyggf2, acyl-CoA dehydrogenase family member 9, mitochondrial, acyl-Coenzyme A dehydrogenase family, member 9
Species: rat
Products:     Acad9

Top Publications

  1. Ghisla S, Thorpe C. Acyl-CoA dehydrogenases. A mechanistic overview. Eur J Biochem. 2004;271:494-508 pubmed
    ..These views are also discussed in the context of the accompanying paper on the three-dimensional properties of acyl-CoA dehydrogenases. ..
  2. Ensenauer R, He M, Willard J, Goetzman E, Corydon T, Vandahl B, et al. Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids. J Biol Chem. 2005;280:32309-16 pubmed
    ..Because of the substrate specificity and abundance of ACAD-9 in brain, we speculate that it may play a role in the turnover of lipid membrane unsaturated fatty acids that are essential for membrane integrity and structure. ..
  3. Nouws J, Nijtmans L, Houten S, van den Brand M, Huynen M, Venselaar H, et al. Acyl-CoA dehydrogenase 9 is required for the biogenesis of oxidative phosphorylation complex I. Cell Metab. 2010;12:283-94 pubmed publisher
    Acyl-CoA dehydrogenase 9 (ACAD9) is a recently identified member of the acyl-CoA dehydrogenase family...
  4. Zeng J, Deng S, Wang Y. Identification of the Catalytic Residue of Rat Acyl-CoA Dehydrogenase 9 by Site-Directed Mutagenesis. Appl Biochem Biotechnol. 2017;182:1198-1207 pubmed publisher
    ..Those results suggested that Glu389 could function as the catalytic base that abstracted the ?-proton of the acyl-CoA substrate in a proposed catalytic mechanism. ..
  5. Roomets E, Kivela T, Tyni T. Carnitine palmitoyltransferase I and Acyl-CoA dehydrogenase 9 in retina: insights of retinopathy in mitochondrial trifunctional protein defects. Invest Ophthalmol Vis Sci. 2008;49:1660-4 pubmed publisher
  6. He M, Pei Z, Mohsen A, Watkins P, Murdoch G, Van Veldhoven P, et al. Identification and characterization of new long chain acyl-CoA dehydrogenases. Mol Genet Metab. 2011;102:418-29 pubmed publisher
    ..The combination of ACAD11 with the newly characterized ACAD9 accommodates the full spectrum of long chain fatty acid substrates presented to mitochondrial ?-oxidation in human ..