sodium dicarboxylate cotransporter


Gene Symbol: sodium dicarboxylate cotransporter
Description: solute carrier family 13 member 2
Alias: INDY, NADC1, NaDC-1, SDCT1, solute carrier family 13 member 2, Na(+)/dicarboxylate cotransporter 1, renal sodium/dicarboxylate cotransporter, sodium/dicarboxylate cotransporter, solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
Species: rabbit

Top Publications

  1. Pajor A. Sequence and functional characterization of a renal sodium/dicarboxylate cotransporter. J Biol Chem. 1995;270:5779-85 pubmed
    ..The results of the functional characterization indicate that NaDC-1 likely corresponds to the renal brush-border Na+/dicarboxylate cotransporter. ..
  2. Pajor A, Sun N, Joshi A, Randolph K. Transmembrane helix 7 in the Na+/dicarboxylate cotransporter 1 is an outer helix that contains residues critical for function. Biochim Biophys Acta. 2011;1808:1454-61 pubmed publisher
    Citric acid cycle intermediates, including succinate and citrate, are absorbed across the apical membrane by the NaDC1 Na+/dicarboxylate cotransporter located in the kidney and small intestine...
  3. Colas C, Schlessinger A, Pajor A. Mapping Functionally Important Residues in the Na+/Dicarboxylate Cotransporter, NaDC1. Biochemistry. 2017;56:4432-4441 pubmed publisher
    ..previously modeled mammalian members of the SLC13 family, including the Na+/dicarboxylate cotransporter NaDC1 (SLC13A2), based on a structure of the bacterial homologue VcINDY in an inward-facing conformation with one sodium ..