SMAD7

Summary

Gene Symbol: SMAD7
Description: SMAD family member 7
Alias: mothers against decapentaplegic homolog 7
Species: rabbit

Top Publications

  1. He X, Gao X, Peng L, Wang S, Zhu Y, Ma H, et al. Atrial fibrillation induces myocardial fibrosis through angiotensin II type 1 receptor-specific Arkadia-mediated downregulation of Smad7. Circ Res. 2011;108:164-75 pubmed publisher
    ..However, the expression of Smad7, a key endogenous antagonist of the TGF-?(1)/Smad-mediated fibrosis, was significantly decreased...
  2. Tsai T, Sun M, Ho T, Ma H, Liu M, Tsao Y. Notch prevents transforming growth factor-beta-assisted epithelial-mesenchymal transition in cultured limbal progenitor cells through the induction of Smad7. Mol Vis. 2014;20:522-34 pubmed
    ..to western blot analysis of TGF? signaling components, including TGF?1, TGF? receptor I/II, and Smad2/3 as well as Smad7, the main negative regulator of TGF? signaling...
  3. He X, Zhang K, Gao X, Li L, Tan H, Chen J, et al. Rapid atrial pacing induces myocardial fibrosis by down-regulating Smad7 via microRNA-21 in rabbit. Heart Vessels. 2016;31:1696-708 pubmed publisher
    ..In our previous study, we found that Smad7-downregulation promoted the development of atrial fibrosis in AF...
  4. Salma U, Xue M, Ali Sheikh M, Guan X, Xu B, Zhang A, et al. Role of Transforming Growth Factor-?1 and Smads Signaling Pathway in Intrauterine Adhesion. Mediators Inflamm. 2016;2016:4158287 pubmed publisher
    The aim of the study was to evaluate the role of Smad3, Smad7, and TGF-?1 in intrauterine adhesion (IUA) patients and experimental rabbit models. 60 IUA patients, 30 control participants, and 18 female rabbits were enrolled in this study...