Gene Symbol: ZP4
Description: zona pellucida glycoprotein 2
Alias: ZPA, Zp-2, zona pellucida sperm-binding protein 2, ZP1, zona pellucida 2 glycoprotein, zona pellucida glycoprotein ZP2, zona pellucida protein A
Species: pig

Top Publications

  1. Hasegawa A, Koyama K, Okazaki Y, Sugimoto M, Isojima S. Amino acid sequence of a porcine zona pellucida glycoprotein ZP4 determined by peptide mapping and cDNA cloning. J Reprod Fertil. 1994;100:245-55 pubmed
    ..In this study, the amino acid sequence of a core protein of porcine zona pellucida glycoprotein ZP4 was determined by peptide mapping and cDNA cloning...
  2. Burkart A, Xiong B, Baibakov B, Jim nez Movilla M, Dean J. Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy. J Cell Biol. 2012;197:37-44 pubmed publisher
    The mouse zona pellucida is composed of three glycoproteins (ZP1, ZP2, and ZP3), of which ZP2 is proteolytically cleaved after gamete fusion to prevent polyspermy...
  3. Yonezawa N, Kudo K, Terauchi H, Kanai S, Yoda N, Tanokura M, et al. Recombinant porcine zona pellucida glycoproteins expressed in Sf9 cells bind to bovine sperm but not to porcine sperm. J Biol Chem. 2005;280:20189-96 pubmed
    The zona pellucida, which surrounds the mammalian oocyte, consists of the ZPA, ZPB, and ZPC glycoproteins and plays roles in species-selective sperm-egg interactions via its carbohydrate moieties...
  4. Taya T, Yamasaki N, Tsubamoto H, Hasegawa A, Koyama K. Cloning of a cDNA coding for porcine zona pellucida glycoprotein ZP1 and its genomic organization. Biochem Biophys Res Commun. 1995;207:790-9 pubmed
    ..Our previous study showed that porcine ZP1, one of the major glycoproteins of porcine zona pellucida, was divided into two components (porcine ZP4 and ZP2), ..