- An intronic insertion in KPL2 results in aberrant splicing and causes the immotile short-tail sperm defect in the pigAnu Sironen
MTT Agrifood Research Finland, Animal Production Research, Animal Breeding, FIN 31600, Jokioinen, Finland
Proc Natl Acad Sci U S A 103:5006-11. 2006..2 containing eight annotated genes. Sequence analysis of a candidate gene KPL2 revealed the presence of an inserted retrotransposon within an intron...
- Infertile Finnish Yorkshire boars carry a full-length LINE-1 retrotransposon within the KPL2 geneAnu Sironen
Food and Biotechnology, Animal Genomics, MTT Agrifood Research Finland, 31600, Jokioinen, Finland
Mol Genet Genomics 278:385-91. 2007The KPL2 gene is expressed predominantly in cells with cilia or flagella. We have previously demonstrated that a large intronic insertion in KPL2 is associated with immotile sperm cells and infertility in the domesticated pig (Sus scrofa)...