Gene Symbol: NFKB1
Description: nuclear factor kappa B subunit 1
Alias: nuclear factor NF-kappa-B p105 subunit, RHD of nuclear factor NF-kappa-B p105 subunit, nuclear factor NF-kappa-B p50 subunit, nuclear factor kappa-B 1, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)
Species: pig
Products:     NFKB1

Top Publications

  1. Kim D, Kim K, Kang J, Jung E, Kim S, Jeung E, et al. Trans-10, cis-12-conjugated linoleic acid modulates NF-?B activation and TNF-? production in porcine peripheral blood mononuclear cells via a PPAR?-dependent pathway. Br J Nutr. 2011;105:1329-36 pubmed publisher
    ..These results suggest that t10c12-CLA can modulate TNF-? production and NF-?B activation by a PPAR?-dependent pathway in porcine PBMC...
  2. Sirotkin A, Dekanová P, Harrath A, Alwasel S, Vasicek D. Interrelationships between sirtuin 1 and transcription factors p53 and NF-?B (p50/p65) in the control of ovarian cell apoptosis and proliferation. Cell Tissue Res. 2014;358:627-32 pubmed publisher
  3. Gao H, Lin L, Haq I, Zeng S. Inhibition of NF-?B promotes autophagy via JNK signaling pathway in porcine granulosa cells. Biochem Biophys Res Commun. 2016;473:311-316 pubmed publisher
    ..Our results provide new insights into the regulation and function of autophagy in mammalian follicle development. ..
  4. Zhang Q, Ma J, Yoo D. Inhibition of NF-?B activity by the porcine epidemic diarrhea virus nonstructural protein 1 for innate immune evasion. Virology. 2017;510:111-126 pubmed publisher
    ..Our study showed that PEDV inhibited NF-?B activity and nsp1 was a potent NF-?B antagonist for suppression of both IFN and early production of pro-inflammatory cytokines. ..
  5. Zhou Y, Jin X, Jing Y, Song Y, He X, Zheng L, et al. Porcine parvovirus infection activates inflammatory cytokine production through Toll-like receptor 9 and NF-κB signaling pathways in porcine kidney cells. Vet Microbiol. 2017;207:56-62 pubmed publisher
    ..Taken together, PPV infection significantly induced IL-6 expression and this induction depended on NF-κB activation and TLR9 signaling pathways in PK-15 cell. ..
  6. Zhang H, Liu C, Cheng S, Wang X, Li W, Charreyre C, et al. Porcine CD74 is involved in the inflammatory response activated by nuclear factor kappa B during porcine circovirus type 2 (PCV-2) infection. Arch Virol. 2013;158:2285-95 pubmed publisher
    ..In general, porcine CD74 significantly enhanced the inflammatory response by regulating the NF-?B signalling pathway during PCV2 infection, which suggests that porcine CD74 may be implicated in the pathogenesis of PCV2 infection. ..