NFATC1

Summary

Gene Symbol: NFATC1
Description: nuclear factor of activated T cells 1
Alias: NF-ATc, NF-ATc1, NFATc, NFATmac, nuclear factor of activated T-cells, cytoplasmic 1, NFAT transcription complex cytosolic component, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, transcription factor NFATmac
Species: pig

Top Publications

  1. Miskin J, Abrams C, Goatley L, Dixon L. A viral mechanism for inhibition of the cellular phosphatase calcineurin. Science. 1998;281:562-5 pubmed
    ..This it does by binding the catalytic subunit of calcineurin and inhibiting calcineurin phosphatase activity. ..
  2. Palgrave C, Gilmour L, Lowden C, Lillico S, Mellencamp M, Whitelaw C. Species-specific variation in RELA underlies differences in NF-?B activity: a potential role in African swine fever pathogenesis. J Virol. 2011;85:6008-14 pubmed publisher
    ..We propose that the variation in RELA identified between the warthog and domestic pig has the potential to underlie the difference between tolerance and rapid death upon ASFV infection...