Gene Symbol: HP
Alias: haptoglobin, haptoglobin alpha 1S, zonulin
Sauerwein H, Schmitz S, Hiss S. The acute phase protein haptoglobin and its relation to oxidative status in piglets undergoing weaning-induced stress. Redox Rep. 2005;10:295-302 pubmed
b>Haptoglobin (Hp) prevents the hemoglobin driven generation of hydroxyl radicals and lipid peroxides. Hp can reduce the neutrophil respiratory burst and is an antioxidative molecule in its own right...
Chung H, Park H, Yoon S, Baek M, Kim J, Kim M. Detection of SNPs in porcine haptoglobin and apolipoprotein genes. Biochem Genet. 2008;46:744-54 pubmed publisher
..spots, differentially expressed in the growth stages, were identified using MALDI-TOF-TOF MS/MS analysis as haptoglobin alpha 1S (Hp) and apolipoprotein A-IV (APOA4) gene products...
Gnanandarajah J, Dvorak C, Johnson C, Murtaugh M. Presence of free haptoglobin alpha 1S-subunit in acute porcine reproductive and respiratory syndrome virus infection. J Gen Virol. 2008;89:2746-53 pubmed publisher
..The 9244+/-2 peak was identified as the alpha 1S (alpha1S)-subunit of porcine haptoglobin (Hp) by tandem MS sequencing and confirmed by immunoblotting with anti-porcine Hp antibody...
Ponsuksili S, Schellander K, Wimmers K. Isolation, polymorphism identification and linkage mapping of the porcine haptoglobin locus. Anim Genet. 2002;33:324-5 pubmed
Segales J, Piñeiro C, Lampreave F, Nofrarias M, Mateu E, Calsamiglia M, et al
. Haptoglobin and pig-major acute protein are increased in pigs with postweaning multisystemic wasting syndrome (PMWS). Vet Res. 2004;35:275-82 pubmed
..objective of this study was to determine the serum concentration levels of selected acute phase proteins (APP), haptoglobin (HPT) and pig-major acute phase protein (pig-MAP), in postweaning multisystemic wasting syndrome (PMWS) ..
Clapperton M, Bishop S, Pineiro M, Campbell F, Glass E. The association between plasma levels of acute phase proteins, haptoglobin, alpha-1 acid glycoprotein (AGP), pig-MAP, transthyretin and serum amyloid A (SAA) in Large White and Meishan pigs. Vet Immunol Immunopathol. 2007;119:303-9 pubmed
..There was a significant correlation between plasma levels of haptoglobin and Pig-MAP (r=0.57; p<0.05), but no significant associations between any of the other APP tested...
Andersen C, Torvund Jensen M, Nielsen M, de Oliveira C, Hersleth H, Andersen N, et al
. Structure of the haptoglobin-haemoglobin complex. Nature. 2012;489:456-9 pubmed publisher
..haemoglobin is released into the plasma, where it is captured by the protective acute-phase protein haptoglobin. This leads to formation of the haptoglobin-haemoglobin complex, which represents a virtually irreversible non-..