high density lipoprotein receptor SR BI


Gene Symbol: high density lipoprotein receptor SR BI
Description: scavenger receptor class B member 1
Alias: scavenger receptor class B member 1, SR-BI, SRB1, high density lipoprotein receptor SR-BI
Species: pig

Top Publications

  1. Kim J, Vallet J, Nonneman D, Christenson R. Molecular cloning and endometrial expression of porcine high density lipoprotein receptor SR-BI during the estrous cycle and early pregnancy. Mol Cell Endocrinol. 2004;222:105-12 pubmed
    ..3 cM on chromosome 14. These results show that endometrial expression of SR-BI changes during the estrous cycle and early pregnancy, and suggest that SR-BI takes up HDL for endometrial development during early pregnancy. ..
  2. Panzenboeck U, Kratzer I, Sovic A, Wintersperger A, Bernhart E, Hammer A, et al. Regulatory effects of synthetic liver X receptor- and peroxisome-proliferator activated receptor agonists on sterol transport pathways in polarized cerebrovascular endothelial cells. Int J Biochem Cell Biol. 2006;38:1314-29 pubmed
    ..Summarizing, in cerebrovascular endothelial cells apoA-I, ABCA1, and SR-BI represent drug targets for LXR and PPAR-agonists to interfere with cholesterol homeostasis at the periphery of the central nervous system...
  3. Goti D, Hrzenjak A, Levak Frank S, Frank S, van der Westhuyzen D, Malle E, et al. Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E. J Neurochem. 2001;76:498-508 pubmed
    ..The results of this study indicate that SR-BI promotes the uptake of HDL-associated alphaTocH into cells constituting the BBB and plays an important role during the supply of the CNS with this indispensable micronutrient. ..
  4. Balazs Z, Panzenboeck U, Hammer A, Sovic A, Quehenberger O, Malle E, et al. Uptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier model. J Neurochem. 2004;89:939-50 pubmed
  5. Miranda Jiménez L, Murphy B. Lipoprotein receptor expression during luteinization of the ovarian follicle. Am J Physiol Endocrinol Metab. 2007;293:E1053-61 pubmed
    ..Expression of the LDL receptor is extinguished during luteinization, indicating dynamic regulation of cholesterol importation to maintain elevated steroid output by the CL. ..