FXYD1

Summary

Gene Symbol: FXYD1
Description: FXYD domain containing ion transport regulator 1
Alias: PLM, phospholemman
Species: pig

Top Publications

  1. ncbi Serine 68 phospholemman phosphorylation during forskolin-induced swine carotid artery relaxation
    Christopher M Rembold
    Cardiovascular Division, Department of Internal Medicine, University of Virginia Health System, Charlottesville, VA 22908, USA
    J Vasc Res 42:483-91. 2005
  2. ncbi Phospholemman does not participate in forskolin-induced swine carotid artery relaxation
    M K Meeks
    Cardiovascular Division, Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia, USA
    Physiol Res 57:669-75. 2008

Research Grants

  1. NO-CGMP INHIBITION OF UROGENITAL SMOOTH MUSCLE
    Christopher Rembold; Fiscal Year: 2004
  2. P20-Mediated Suppression of Vascular Force
    Christopher Rembold; Fiscal Year: 2004

Scientific Experts

Detail Information

Publications2

  1. ncbi Serine 68 phospholemman phosphorylation during forskolin-induced swine carotid artery relaxation
    Christopher M Rembold
    Cardiovascular Division, Department of Internal Medicine, University of Virginia Health System, Charlottesville, VA 22908, USA
    J Vasc Res 42:483-91. 2005
    b>Phospholemman (PLM) is an abundant phosphoprotein in the plasma membrane of cardiac, skeletal and smooth muscle. It is a member of the FXYD family of proteins that bind to and regulate the Na,K-ATPase...
  2. ncbi Phospholemman does not participate in forskolin-induced swine carotid artery relaxation
    M K Meeks
    Cardiovascular Division, Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia, USA
    Physiol Res 57:669-75. 2008
    Phosphorylation of phospholemman (PLM) on ser68 has been proposed to at least partially mediate cyclic AMP (cAMP) mediated relaxation of arterial smooth muscle...

Research Grants4

  1. NO-CGMP INHIBITION OF UROGENITAL SMOOTH MUSCLE
    Christopher Rembold; Fiscal Year: 2004
    ....
  2. P20-Mediated Suppression of Vascular Force
    Christopher Rembold; Fiscal Year: 2004
    ..Many current treatments target smooth muscle to reduce tone. It is possible that targeting the force suppression pathway (i.e. p20) might provide comparable benefits. ..