BST2

Summary

Gene Symbol: BST2
Description: bone marrow stromal cell antigen 2
Alias: bone marrow stromal antigen 2, tetherin
Species: pig

Top Publications

  1. Wang X, Li C, Zhou L, Zhang N, Wang X, Ge X, et al. Porcine reproductive and respiratory syndrome virus counteracts the porcine intrinsic virus restriction factors-IFITM1 and Tetherin in MARC-145 cells. Virus Res. 2014;191:92-100 pubmed publisher
    ..3 (Nsp3) or envelope (E) protein of PRRSV interacted with porcine intrinsic virus-restriction factor IFITM1 or Tetherin. Next, in PRRSV-infected MARC-145 cells and the transfected cells with the IFITM1- or Tetherin-expressing plasmid,..
  2. Gupta R, Mlcochova P, Pelchen Matthews A, Petit S, Mattiuzzo G, Pillay D, et al. Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration. Proc Natl Acad Sci U S A. 2009;106:20889-94 pubmed publisher
    b>Tetherin is an IFN-inducible restriction factor that inhibits HIV-1 particle release in the absence of the HIV-1 countermeasure, viral protein U (Vpu)...
  3. Zhang T, Zhao X, Cao G, Zhang Z, Chang W. [Molecular cloning and expression of bone marrow stromal antigen-2 and detection of its biological activity]. Bing Du Xue Bao. 2012;28:548-53 pubmed
    ..In conclusion, the research paves the way for further research on bioactivity assayand antiviral medication. ..
  4. Kong N, Meng Q, Wu Y, Wang Z, Zuo Y, Tong W, et al. Monoclonal Antibody to Bone Marrow Stromal Cell Antigen 2 Protein of Swine. Monoclon Antib Immunodiagn Immunother. 2016;35:172-6 pubmed publisher
    ..The specific MAb of porcine BST-2 provides a valuable tool for further studies of BST-2 to restrict virus infection. ..
  5. . Monoclonal Antibody Against Bone Marrow Stromal Cell Antigen 2 Protein of Swine. Monoclon Antib Immunodiagn Immunother. 2016;35:178 pubmed publisher